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Page 1
Understanding cell fate acquisition in stem-cell-derived pancreatic islets using single-cell multiome-inferred regulomes.
Zhu H, Wang G, Nguyen-Ngoc KV, Kim D, Miller M, Goss G, Kovsky J, Harrington AR, Saunders DC, Hopkirk AL, Melton R, Powers AC, Preissl S, Spagnoli FM, Gaulton KJ, Sander M. Zhu H, et al. Among authors: hopkirk al. Dev Cell. 2023 May 8;58(9):727-743.e11. doi: 10.1016/j.devcel.2023.03.011. Epub 2023 Apr 10. Dev Cell. 2023. PMID: 37040771 Free PMC article.
Genetic risk converges on regulatory networks mediating early type 2 diabetes.
Walker JT, Saunders DC, Rai V, Chen HH, Orchard P, Dai C, Pettway YD, Hopkirk AL, Reihsmann CV, Tao Y, Fan S, Shrestha S, Varshney A, Petty LE, Wright JJ, Ventresca C, Agarwala S, Aramandla R, Poffenberger G, Jenkins R, Mei S, Hart NJ, Phillips S, Kang H, Greiner DL, Shultz LD, Bottino R, Liu J, Below JE; HPAP Consortium; Parker SCJ, Powers AC, Brissova M. Walker JT, et al. Among authors: hopkirk al. Nature. 2023 Dec;624(7992):621-629. doi: 10.1038/s41586-023-06693-2. Epub 2023 Dec 4. Nature. 2023. PMID: 38049589 Free PMC article.
Heterogeneous endocrine cell composition defines human islet functional phenotypes.
Evans-Molina C, Pettway YD, Saunders DC, Sharp SA, Bate TS, Sun H, Durai H, Mei S, Coldren A, Davis C, Reihsmann CV, Hopkirk AL, Taylor J, Bradley A, Aramandla R, Poffenberger G, Eskaros A, Jenkins R, Shi D, Kang H, Rajesh V, Thaman S, Feng F, Cartailler JP, Powers AC, Abraham K, Gloyn AL, Niland JC, Brissova M. Evans-Molina C, et al. Among authors: hopkirk al. bioRxiv [Preprint]. 2024 Nov 21:2024.11.20.623809. doi: 10.1101/2024.11.20.623809. bioRxiv. 2024. PMID: 39605606 Free PMC article. Preprint.
Mapping histological and functional maturation of human endocrine pancreas across early postnatal periods.
Saunders DC, Hart N, Pan FC, Reihsmann CV, Hopkirk AL, Izmaylov N, Mei S, Sherrod BA, Davis C, Duryea J, Haliyur R, Aramandla R, Durai H, Poffenberger G, Martin A, Posgai AL, Kusmartseva I, Beery ML, Yang M, Kang H, Greiner DL, Shultz LD, Cartailler JP, Aamodt KI, Bottino R, Atkinson MA, Wright CVE, Powers AC, Brissova M. Saunders DC, et al. Among authors: hopkirk al. bioRxiv [Preprint]. 2024 Dec 22:2024.12.20.629754. doi: 10.1101/2024.12.20.629754. bioRxiv. 2024. PMID: 39763926 Free PMC article. Preprint.