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Paediatric excipient risk assessment (PERA) tool and application for selecting appropriate excipients for paediatric dosage forms - Part 2.
Agrawal A, Salunke S, Rumondor A, Thompson K, Caivano G, Walsh J, Enright B, Sherratt P, Hughes K, Clapham D, Kuehl P; International Consortium (IQ) for Innovation and Quality in Pharmaceutical Development and European Paediatric Formulation Initiative (EuPFI). Agrawal A, et al. Among authors: kuehl p. Eur J Pharm Biopharm. 2024 Oct;203:114447. doi: 10.1016/j.ejpb.2024.114447. Epub 2024 Aug 8. Eur J Pharm Biopharm. 2024. PMID: 39122051 Free article.
Discovery of GS-7682, a Novel 4'-Cyano-Modified C-Nucleoside Prodrug with Broad Activity against Pneumo- and Picornaviruses and Efficacy in RSV-Infected African Green Monkeys.
Siegel DS, Hui HC, Pitts J, Vermillion MS, Ishida K, Rautiola D, Keeney M, Irshad H, Zhang L, Chun K, Chin G, Goyal B, Doerffler E, Yang H, Clarke MO, Palmiotti C, Vijjapurapu A, Riola NC, Stray K, Murakami E, Ma B, Wang T, Zhao X, Xu Y, Lee G, Marchand B, Seung M, Nayak A, Tomkinson A, Kadrichu N, Ellis S, Barauskas O, Feng JY, Perry JK, Perron M, Bilello JP, Kuehl PJ, Subramanian R, Cihlar T, Mackman RL. Siegel DS, et al. Among authors: kuehl pj. J Med Chem. 2024 Aug 8;67(15):12945-12968. doi: 10.1021/acs.jmedchem.4c00899. Epub 2024 Jul 17. J Med Chem. 2024. PMID: 39018526
Practical Considerations in Dose Extrapolation from Animals to Humans.
Hickey AJ, Maloney SE, Kuehl PJ, Phillips JE, Wolff RK. Hickey AJ, et al. Among authors: kuehl pj. J Aerosol Med Pulm Drug Deliv. 2024 Apr;37(2):77-89. doi: 10.1089/jamp.2023.0041. Epub 2024 Jan 17. J Aerosol Med Pulm Drug Deliv. 2024. PMID: 38237032 Review.
iBCS: 3. A Biopharmaceutics Classification System for Orally Inhaled Drug Products.
Hastedt JE, Bäckman P, Cabal A, Clark A, Ehrhardt C, Forbes B, Hickey AJ, Hochhaus G, Jiang W, Kassinos S, Kuehl PJ, Prime D, Son YJ, Teague S, Tehler U, Wylie J. Hastedt JE, et al. Among authors: kuehl pj. Mol Pharm. 2024 Jan 1;21(1):164-172. doi: 10.1021/acs.molpharmaceut.3c00685. Epub 2023 Dec 7. Mol Pharm. 2024. PMID: 38059771 Free PMC article.
Guidance on Mitigating the Risk of Transmitting Respiratory Infections During Nebulization by the COPD Foundation Nebulizer Consortium.
Biney IN, Ari A, Barjaktarevic IZ, Carlin B, Christiani DC, Cochran L, Drummond MB, Johnson K, Kealing D, Kuehl PJ, Li J, Mahler DA, Martinez S, Ohar J, Radonovich LJ, Sood A, Suggett J, Tal-Singer R, Tashkin D, Yates J, Cambridge L, Dailey PA, Mannino DM, Dhand R. Biney IN, et al. Among authors: kuehl pj. Chest. 2024 Mar;165(3):653-668. doi: 10.1016/j.chest.2023.11.013. Epub 2023 Nov 15. Chest. 2024. PMID: 37977263 Free article.
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