Piro AS - Search Results

1

LPS-aggregating proteins GBP1 and GBP2 are each sufficient to enhance caspase-4 activation both in cellulo and in vitro.

Dickinson MS, Kutsch M, Sistemich L, Hernandez D, Piro AS, Needham D, Lesser CF, Herrmann C, Coers J. Dickinson MS, et al. Among authors: piro as. Proc Natl Acad Sci U S A. 2023 Apr 11;120(15):e2216028120. doi: 10.1073/pnas.2216028120. Epub 2023 Apr 6. Proc Natl Acad Sci U S A. 2023. PMID: 37023136 Free PMC article.

2

Detection of Cytosolic Shigella flexneri via a C-Terminal Triple-Arginine Motif of GBP1 Inhibits Actin-Based Motility.

Piro AS, Hernandez D, Luoma S, Feeley EM, Finethy R, Yirga A, Frickel EM, Lesser CF, Coers J. Piro AS, et al. mBio. 2017 Dec 12;8(6):e01979-17. doi: 10.1128/mBio.01979-17. mBio. 2017. PMID: 29233899 Free PMC article.

3

Dynamin-related Irgm proteins modulate LPS-induced caspase-11 activation and septic shock.

Finethy R, Dockterman J, Kutsch M, Orench-Rivera N, Wallace GD, Piro AS, Luoma S, Haldar AK, Hwang S, Martinez J, Kuehn MJ, Taylor GA, Coers J. Finethy R, et al. Among authors: piro as. EMBO Rep. 2020 Nov 5;21(11):e50830. doi: 10.15252/embr.202050830. Epub 2020 Oct 30. EMBO Rep. 2020. PMID: 33124745 Free PMC article.

4

Ubiquitin systems mark pathogen-containing vacuoles as targets for host defense by guanylate binding proteins.

Haldar AK, Foltz C, Finethy R, Piro AS, Feeley EM, Pilla-Moffett DM, Komatsu M, Frickel EM, Coers J. Haldar AK, et al. Among authors: piro as. Proc Natl Acad Sci U S A. 2015 Oct 13;112(41):E5628-37. doi: 10.1073/pnas.1515966112. Epub 2015 Sep 28. Proc Natl Acad Sci U S A. 2015. PMID: 26417105 Free PMC article.

5

Galectin-3 directs antimicrobial guanylate binding proteins to vacuoles furnished with bacterial secretion systems.

Feeley EM, Pilla-Moffett DM, Zwack EE, Piro AS, Finethy R, Kolb JP, Martinez J, Brodsky IE, Coers J. Feeley EM, et al. Among authors: piro as. Proc Natl Acad Sci U S A. 2017 Feb 28;114(9):E1698-E1706. doi: 10.1073/pnas.1615771114. Epub 2017 Feb 13. Proc Natl Acad Sci U S A. 2017. PMID: 28193861 Free PMC article.

6

A Rapidly Evolving Polybasic Motif Modulates Bacterial Detection by Guanylate Binding Proteins.

Kohler KM, Kutsch M, Piro AS, Wallace GD, Coers J, Barber MF. Kohler KM, et al. Among authors: piro as. mBio. 2020 May 19;11(3):e00340-20. doi: 10.1128/mBio.00340-20. mBio. 2020. PMID: 32430466 Free PMC article.

7

The E2-like conjugation enzyme Atg3 promotes binding of IRG and Gbp proteins to Chlamydia- and Toxoplasma-containing vacuoles and host resistance.

Haldar AK, Piro AS, Pilla DM, Yamamoto M, Coers J. Haldar AK, et al. Among authors: piro as. PLoS One. 2014 Jan 17;9(1):e86684. doi: 10.1371/journal.pone.0086684. eCollection 2014. PLoS One. 2014. PMID: 24466199 Free PMC article.

8

Human GBP1 does not localize to pathogen vacuoles but restricts Toxoplasma gondii.

Johnston AC, Piro A, Clough B, Siew M, Virreira Winter S, Coers J, Frickel EM. Johnston AC, et al. Cell Microbiol. 2016 Aug;18(8):1056-64. doi: 10.1111/cmi.12579. Epub 2016 Mar 10. Cell Microbiol. 2016. PMID: 26874079 Free PMC article.

9

IRG and GBP host resistance factors target aberrant, "non-self" vacuoles characterized by the missing of "self" IRGM proteins.

Haldar AK, Saka HA, Piro AS, Dunn JD, Henry SC, Taylor GA, Frickel EM, Valdivia RH, Coers J. Haldar AK, et al. Among authors: piro as. PLoS Pathog. 2013;9(6):e1003414. doi: 10.1371/journal.ppat.1003414. Epub 2013 Jun 13. PLoS Pathog. 2013. PMID: 23785284 Free PMC article.

10

Chlamydia trachomatis Is Resistant to Inclusion Ubiquitination and Associated Host Defense in Gamma Interferon-Primed Human Epithelial Cells.

Haldar AK, Piro AS, Finethy R, Espenschied ST, Brown HE, Giebel AM, Frickel EM, Nelson DE, Coers J. Haldar AK, et al. Among authors: piro as. mBio. 2016 Dec 13;7(6):e01417-16. doi: 10.1128/mBio.01417-16. mBio. 2016. PMID: 27965446 Free PMC article.

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