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5,397 results

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Novel gut-based pharmacology of metformin in patients with type 2 diabetes mellitus.
Napolitano A, Miller S, Nicholls AW, Baker D, Van Horn S, Thomas E, Rajpal D, Spivak A, Brown JR, Nunez DJ. Napolitano A, et al. Among authors: thomas e. PLoS One. 2014 Jul 2;9(7):e100778. doi: 10.1371/journal.pone.0100778. eCollection 2014. PLoS One. 2014. PMID: 24988476 Free PMC article. Clinical Trial.
Microbiome changes in healthy volunteers treated with GSK1322322, a novel antibiotic targeting bacterial peptide deformylase.
Arat S, Spivak A, Van Horn S, Thomas E, Traini C, Sathe G, Livi GP, Ingraham K, Jones L, Aubart K, Holmes DJ, Naderer O, Brown JR. Arat S, et al. Among authors: thomas e. Antimicrob Agents Chemother. 2015 Feb;59(2):1182-92. doi: 10.1128/AAC.04506-14. Epub 2014 Dec 8. Antimicrob Agents Chemother. 2015. PMID: 25487798 Free PMC article. Clinical Trial.
Lysine specific demethylase 1 inactivation enhances differentiation and promotes cytotoxic response when combined with all-trans retinoic acid in acute myeloid leukemia across subtypes.
Smitheman KN, Severson TM, Rajapurkar SR, McCabe MT, Karpinich N, Foley J, Pappalardi MB, Hughes A, Halsey W, Thomas E, Traini C, Federowicz KE, Laraio J, Mobegi F, Ferron-Brady G, Prinjha RK, Carpenter CL, Kruger RG, Wessels L, Mohammad HP. Smitheman KN, et al. Among authors: thomas e. Haematologica. 2019 Jun;104(6):1156-1167. doi: 10.3324/haematol.2018.199190. Epub 2018 Dec 4. Haematologica. 2019. PMID: 30514804 Free PMC article.
Preclinical Characterization and In Vivo Efficacy of GSK8853, a Small-Molecule Inhibitor of the Hepatitis C Virus NS4B Protein.
Pouliot JJ, Thomson M, Xie M, Horton J, Johnson J, Krull D, Mathis A, Morikawa Y, Parks D, Peterson R, Shimada T, Thomas E, Vamathevan J, Van Horn S, Xiong Z, Hamatake R, Peat AJ. Pouliot JJ, et al. Among authors: thomas e. Antimicrob Agents Chemother. 2015 Oct;59(10):6539-50. doi: 10.1128/AAC.00813-15. Epub 2015 Aug 10. Antimicrob Agents Chemother. 2015. PMID: 26259798 Free PMC article.
Temporal and spatial distribution of clonal complexes of Streptococcus pneumoniae isolates resistant to multiple classes of antibiotics in Belgium, 1997 to 2004.
Amrine-Madsen H, Van Eldere J, Mera RM, Miller LA, Poupard JA, Thomas ES, Halsey WS, Becker JA, O'Hara FP. Amrine-Madsen H, et al. Antimicrob Agents Chemother. 2008 Sep;52(9):3216-20. doi: 10.1128/AAC.00358-08. Epub 2008 Jun 23. Antimicrob Agents Chemother. 2008. PMID: 18573928 Free PMC article.
Bacterial resistance to leucyl-tRNA synthetase inhibitor GSK2251052 develops during treatment of complicated urinary tract infections.
O'Dwyer K, Spivak AT, Ingraham K, Min S, Holmes DJ, Jakielaszek C, Rittenhouse S, Kwan AL, Livi GP, Sathe G, Thomas E, Van Horn S, Miller LA, Twynholm M, Tomayko J, Dalessandro M, Caltabiano M, Scangarella-Oman NE, Brown JR. O'Dwyer K, et al. Among authors: thomas e. Antimicrob Agents Chemother. 2015 Jan;59(1):289-98. doi: 10.1128/AAC.03774-14. Epub 2014 Oct 27. Antimicrob Agents Chemother. 2015. PMID: 25348524 Free PMC article. Clinical Trial.
5,397 results