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Gene therapy restores the transcriptional program of hematopoietic stem cells in Fanconi anemia.
Lasaga M, Río P, Vilas-Zornoza A, Planell N, Navarro S, Alignani D, Fernández-Varas B, Mouzo D, Zubicaray J, Pujol RM, Nicoletti E, Schwartz JD, Sevilla J, Ainciburi M, Ullate-Agote A, Surrallés J, Perona R, Sastre L, Prosper F, Gomez-Cabrero D, Bueren JA. Lasaga M, et al. Among authors: perona r. Haematologica. 2023 Oct 1;108(10):2652-2663. doi: 10.3324/haematol.2022.282418. Haematologica. 2023. PMID: 37021532 Free PMC article.
Clinical mutations in the TERT and TERC genes coding for telomerase components induced oxidative stress, DNA damage at telomeres and cell apoptosis besides decreased telomerase activity.
Fernández-Varas B, Manguan-García C, Rodriguez-Centeno J, Mendoza-Lupiáñez L, Calatayud J, Perona R, Martín-Martínez M, Gutierrez-Rodriguez M, Benítez-Buelga C, Sastre L. Fernández-Varas B, et al. Among authors: perona r. Hum Mol Genet. 2024 Apr 18;33(9):818-834. doi: 10.1093/hmg/ddae015. Hum Mol Genet. 2024. PMID: 38641551 Free PMC article.
DUSP1 and SOX2 expression determine squamous cell carcinoma of the salivary gland progression.
Acero-Riaguas L, Griso-Acevedo AB, SanLorenzo-Vaquero A, Ibáñez-Herrera B, Fernandez-Diaz SM, Mascaraque M, Sánchez-Siles R, López-García I, Benítez-Buelga C, Bravo-Burguillos ER, Castelo B, Cebrián-Carretero JL, Perona R, Sastre L, Sastre-Perona A. Acero-Riaguas L, et al. Among authors: perona r. Sci Rep. 2024 Jul 1;14(1):15007. doi: 10.1038/s41598-024-65945-x. Sci Rep. 2024. PMID: 38951654 Free PMC article.
Diagnostic and prognostic implications of family history of fibrotic interstitial lung diseases.
Duminy-Luppi D, Alcaide-Aldeano A, Planas-Cerezales L, Bermudo G, Vicens-Zygmunt V, Luburich P, Del Río-Carrero B, Llatjós R, Pijuan L, Escobar I, Rivas F, Montes-Worboys A, Gutiérrez-Rodríguez Y, Rodríguez-Plaza D, Padró-Miquel A, Esteve-Garcia A, Fernández-Varas B, Flores C, Fuentes M, Dorca J, Santos S, Perona R, Günther A, Shull J, Molina-Molina M. Duminy-Luppi D, et al. Among authors: perona r. Respir Res. 2024 Dec 18;25(1):433. doi: 10.1186/s12931-024-03063-y. Respir Res. 2024. PMID: 39695595 Free PMC article.
A crowdsourcing database for the copy-number variation of the Spanish population.
López-López D, Roldán G, Fernández-Rueda JL, Bostelmann G, Carmona R, Aquino V, Perez-Florido J, Ortuño F, Pita G, Núñez-Torres R, González-Neira A; CSVS Crowdsourcing Group; Peña-Chilet M, Dopazo J. López-López D, et al. Hum Genomics. 2023 Mar 9;17(1):20. doi: 10.1186/s40246-023-00466-8. Hum Genomics. 2023. PMID: 36894999 Free PMC article.
Platinum iodido drugs show potential anti-tumor activity, affecting cancer cell metabolism and inducing ROS and senescence in gastrointestinal cancer cells.
Melones-Herrero J, Alcalá S, Ruiz-Cañas L, Benítez-Buelga C, Batres-Ramos S, Calés C, Lorenzo O, Perona R, Quiroga AG, Sainz B Jr, Sánchez-Pérez I. Melones-Herrero J, et al. Among authors: perona r. Commun Biol. 2024 Mar 22;7(1):353. doi: 10.1038/s42003-024-06052-5. Commun Biol. 2024. PMID: 38519773 Free PMC article.
Regulatory effects of miR-19a on MAD2 expression and tumorigenesis in gastric cancer.
Bargiela-Iparraguirre J, Herrero JM, Pajuelo-Lozano N, Perez M, Perona R, Quiroga AG, Calés C, Sanchez-Perez I. Bargiela-Iparraguirre J, et al. Among authors: perona r. Genes Dis. 2023 Mar 27;10(4):1180-1182. doi: 10.1016/j.gendis.2023.02.025. eCollection 2023 Jul. Genes Dis. 2023. PMID: 37397556 Free PMC article. No abstract available.
130 results