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Sex and Common Germline Variants Affect the Toxicity Profile and Pharmacokinetics of Alectinib: A Nationwide Cohort Study in Patients With ALK-Positive NSCLC.
Heersche N, Lanser DAC, Muntinghe-Wagenaar MB, Mohmaed Ali MI, Ulas EB, Trooster TMA, de Jonge E, Oomen-de Hoop E, Paats MS, Bahce I, Croes S, Hendriks LEL, van der Wekken AJ, Dingemans AC, Huitema ADR, van Schaik RHN, Mathijssen RHJ, Veerman GDM. Heersche N, et al. Among authors: huitema adr. J Thorac Oncol. 2024 Nov 29:S1556-0864(24)02488-2. doi: 10.1016/j.jtho.2024.11.025. Online ahead of print. J Thorac Oncol. 2024. PMID: 39617342 Free article.
Development and validation of ultra-performance liquid chromatography tandem mass spectrometry methods for the quantitative analysis of the antiparasitic drug DNDI-6148 in human plasma and various mouse biomatrices.
Schouten WM, Van Bocxlaer K, Rosing H, Huitema ADR, Beijnen JH, Kratz JM, Mowbray CE, Dorlo TPC. Schouten WM, et al. Among authors: huitema adr. J Chromatogr B Analyt Technol Biomed Life Sci. 2025 Jan 1;1250:124377. doi: 10.1016/j.jchromb.2024.124377. Epub 2024 Nov 12. J Chromatogr B Analyt Technol Biomed Life Sci. 2025. PMID: 39577310 Free article.
A Population Pharmacokinetic Study to Evaluate Doxorubicin Exposure Across All Age Groups.
Mohmaed Ali MI, Nijstad AL, Boosman RJ, Crombag MBS, Barnett S, Veal GJ, Lalmohamed A, van Erp NP, Steeghs N, Zwaan CM, Beijnen JH, Siebinga H, Huitema ADR. Mohmaed Ali MI, et al. Among authors: huitema adr. Clin Pharmacokinet. 2024 Dec;63(12):1711-1722. doi: 10.1007/s40262-024-01445-5. Epub 2024 Nov 16. Clin Pharmacokinet. 2024. PMID: 39549227
Platinum retention in plasma, urine, and normal colonic mucosa in cisplatin-treated testicular cancer survivors.
Breekveldt ECH, Ykema BLM, Huitema ADR, Gietema JA, Beijnen JH, Snaebjornsson P, Schaapveld M, van Leeuwen FE, Rosing H, van Leerdam ME; CATCHER study working group. Breekveldt ECH, et al. Among authors: huitema adr. PLoS One. 2024 Nov 14;19(11):e0312994. doi: 10.1371/journal.pone.0312994. eCollection 2024. PLoS One. 2024. PMID: 39541403 Free PMC article.
509 results