Bruin MAC - Search Results

1

Radiosensitisation by olaparib through focused ultrasound delivery in a diffuse midline glioma model.

't Hart E, Bianco J, Bruin MAC, Derieppe M, Besse HC, Berkhout K, Chin Joe Kie LA, Su Y, Hoving EW, Huitema ADR, Ries MG, van Vuurden DG. 't Hart E, et al. Among authors: bruin mac. J Control Release. 2023 May;357:287-298. doi: 10.1016/j.jconrel.2023.03.058. Epub 2023 Apr 5. J Control Release. 2023. PMID: 37019285 Free article.

2

Development and validation of an LC-MS/MS method with a broad linear dynamic range for the quantification of tivozanib in human and mouse plasma, mouse tissue homogenates, and culture medium.

Bruin MAC, Rosing H, Lucas L, Wang J, Huitema ADR, Schinkel AH, Beijnen JH. Bruin MAC, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2019 Sep 1;1125:121723. doi: 10.1016/j.jchromb.2019.121723. Epub 2019 Jul 18. J Chromatogr B Analyt Technol Biomed Life Sci. 2019. PMID: 31352204

3

Development and validation of an integrated LC-MS/MS assay for therapeutic drug monitoring of five PARP-inhibitors.

Bruin MAC, de Vries N, Lucas L, Rosing H, Huitema ADR, Beijnen JH. Bruin MAC, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2020 Feb 1;1138:121925. doi: 10.1016/j.jchromb.2019.121925. Epub 2019 Dec 6. J Chromatogr B Analyt Technol Biomed Life Sci. 2020. PMID: 31915109

4

Toxicological analysis of azide and cyanide for azide intoxications using gas chromatography.

Bruin MAC, Dekker D, Venekamp N, Tibben M, Rosing H, de Lange DW, Beijnen JH, Huitema ADR. Bruin MAC, et al. Basic Clin Pharmacol Toxicol. 2021 Mar;128(3):534-541. doi: 10.1111/bcpt.13523. Epub 2020 Nov 3. Basic Clin Pharmacol Toxicol. 2021. PMID: 33090684 Free PMC article.

5

A real or apparent decrease in glomerular filtration rate in patients using olaparib?

Bruin MAC, Korse CM, van Wijnen B, de Jong VMT, Linn SC, van Triest B, Rosing H, Beijnen JH, van den Broek D, Huitema ADR. Bruin MAC, et al. Eur J Clin Pharmacol. 2021 Feb;77(2):179-188. doi: 10.1007/s00228-020-03070-0. Epub 2020 Dec 14. Eur J Clin Pharmacol. 2021. PMID: 33319340 Free PMC article.

6

Pharmacokinetics and Pharmacodynamics of PARP Inhibitors in Oncology.

Bruin MAC, Sonke GS, Beijnen JH, Huitema ADR. Bruin MAC, et al. Clin Pharmacokinet. 2022 Dec;61(12):1649-1675. doi: 10.1007/s40262-022-01167-6. Epub 2022 Oct 11. Clin Pharmacokinet. 2022. PMID: 36219340 Free PMC article. Review.

7

Exposure-Response Analyses of Olaparib in Real-Life Patients with Ovarian Cancer.

Mohmaed Ali MI, Bruin MAC, Dezentjé VO, Beijnen JH, Steeghs N, Huitema ADR. Mohmaed Ali MI, et al. Among authors: bruin mac. Pharm Res. 2023 May;40(5):1239-1247. doi: 10.1007/s11095-023-03497-x. Epub 2023 Mar 22. Pharm Res. 2023. PMID: 36944815

8

Cortisol as Biomarker for CYP17-Inhibition is Associated with Therapy Outcome of Abiraterone Acetate.

Bruin MAC, Mohmaed Ali MI, van Nuland M, Jacobs BAW, Lucas L, Dezentje VO, de Feijter JM, Rosing H, Bergman AM, Beijnen JH, Huitema ADR. Bruin MAC, et al. Pharm Res. 2023 Dec;40(12):3001-3010. doi: 10.1007/s11095-023-03615-9. Epub 2023 Oct 11. Pharm Res. 2023. PMID: 37821768

9

Brain accumulation of tivozanib is restricted by ABCB1 (P-glycoprotein) and ABCG2 (breast cancer resistance protein) in mice.

Wang J, Bruin MAC, Gan C, Lebre MC, Rosing H, Beijnen JH, Schinkel AH. Wang J, et al. Among authors: bruin mac. Int J Pharm. 2020 May 15;581:119277. doi: 10.1016/j.ijpharm.2020.119277. Epub 2020 Mar 28. Int J Pharm. 2020. PMID: 32234426

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