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PIEZO1 and PECAM1 interact at cell-cell junctions and partner in endothelial force sensing.
Chuntharpursat-Bon E, Povstyan OV, Ludlow MJ, Carrier DJ, Debant M, Shi J, Gaunt HJ, Bauer CC, Curd A, Simon Futers T, Baxter PD, Peckham M, Muench SP, Adamson A, Humphreys N, Tumova S, Bon RS, Cubbon R, Lichtenstein L, Beech DJ. Chuntharpursat-Bon E, et al. Among authors: humphreys n. Commun Biol. 2023 Apr 1;6(1):358. doi: 10.1038/s42003-023-04706-4. Commun Biol. 2023. PMID: 37005489 Free PMC article.
RAC1B function is essential for breast cancer stem cell maintenance and chemoresistance of breast tumor cells.
Chen F, Gurler SB, Novo D, Selli C, Alferez DG, Eroglu S, Pavlou K, Zhang J, Sims AH, Humphreys NE, Adamson A, Campbell A, Sansom OJ, Tournier C, Clarke RB, Brennan K, Streuli CH, Ucar A. Chen F, et al. Among authors: humphreys ne. Oncogene. 2023 Feb;42(9):679-692. doi: 10.1038/s41388-022-02574-6. Epub 2023 Jan 5. Oncogene. 2023. PMID: 36599922 Free PMC article.
A rare human variant that disrupts GPR10 signalling causes weight gain in mice.
Talbot F, Feetham CH, Mokrosiński J, Lawler K, Keogh JM, Henning E, Mendes de Oliveira E, Ayinampudi V, Saeed S, Bonnefond A, Arslan M, Yeo GSH, Froguel P, Bechtold DA, Adamson A, Humphreys N, Barroso I, Luckman SM, Farooqi IS. Talbot F, et al. Among authors: humphreys n. Nat Commun. 2023 Mar 15;14(1):1450. doi: 10.1038/s41467-023-36966-3. Nat Commun. 2023. PMID: 36922513 Free PMC article.
A new knockin mouse carrying the E364X patient mutation for CDKL5 deficiency disorder: neurological, behavioral and molecular profiling.
Quadalti C, Sannia M, Humphreys NE, Baldassarro VA, Gurgone A, Ascolani M, Zanella L, Giardino L, Gross CT, Croci S, Meloni I, Giustetto M, Renieri A, Lorenzini L, Calzà L. Quadalti C, et al. Among authors: humphreys ne. Heliyon. 2024 Nov 6;10(21):e40165. doi: 10.1016/j.heliyon.2024.e40165. eCollection 2024 Nov 15. Heliyon. 2024. PMID: 39583831 Free PMC article.
Serosurvey for Japanese encephalitis virus antibodies following an outbreak in an immunologically naïve population, Victoria, 2022: a cross-sectional study.
Marsland MJ, Thomson TN, O'Brien HM, Peach E, Bellette J, Humphreys N, McKeon CA, Cross W, Moso MA, Batty M, Nicholson S, Karapanagiotidis T, Lim CK, Williamson DA, Winkler N, Koirala A, Macartney K, Glynn-Robinson A, Stewart T, Minko C, Snow KJ, Black J, Friedman ND. Marsland MJ, et al. Among authors: humphreys n. Med J Aust. 2024 Jun 17;220(11):566-572. doi: 10.5694/mja2.52344. Epub 2024 May 27. Med J Aust. 2024. PMID: 38803004
Paternal microbiome perturbations impact offspring fitness.
Argaw-Denboba A, Schmidt TSB, Di Giacomo M, Ranjan B, Devendran S, Mastrorilli E, Lloyd CT, Pugliese D, Paribeni V, Dabin J, Pisaniello A, Espinola S, Crevenna A, Ghosh S, Humphreys N, Boruc O, Sarkies P, Zimmermann M, Bork P, Hackett JA. Argaw-Denboba A, et al. Among authors: humphreys n. Nature. 2024 May;629(8012):652-659. doi: 10.1038/s41586-024-07336-w. Epub 2024 May 1. Nature. 2024. PMID: 38693261 Free PMC article.
Independent endothelial functions of PIEZO1 and TRPV4 in hepatic portal vein and predominance of PIEZO1 in mechanical and osmotic stress.
Endesh N, Chuntharpursat-Bon E, Revill C, Yuldasheva NY, Futers TS, Parsonage G, Humphreys N, Adamson A, Morley LC, Cubbon RM, Prasad KR, Foster R, Lichtenstein L, Beech DJ. Endesh N, et al. Among authors: humphreys n. Liver Int. 2023 Sep;43(9):2026-2038. doi: 10.1111/liv.15646. Epub 2023 Jun 22. Liver Int. 2023. PMID: 37349903 Free PMC article.
63 results