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Generation and multi-dimensional profiling of a childhood cancer cell line atlas defines new therapeutic opportunities.
Sun CX, Daniel P, Bradshaw G, Shi H, Loi M, Chew N, Parackal S, Tsui V, Liang Y, Koptyra M, Adjumain S, Sun C, Chong WC, Fernando D, Drinkwater C, Tourchi M, Habarakada D, Sooraj D, Carvalho D, Storm PB, Baubet V, Sayles LC, Fernandez E, Nguyen T, Pörksen M, Doan A, Crombie DE, Panday M, Zhukova N, Dun MD, Ludlow LE, Day B, Stringer BW, Neeman N, Rubens JA, Raabe EH, Vinci M, Tyrrell V, Fletcher JI, Ekert PG, Dumevska B, Ziegler DS, Tsoli M, Syed Sulaiman NF, Loh AHP, Low SYY, Sweet-Cordero EA, Monje M, Resnick A, Jones C, Downie P, Williams B, Rosenbluh J, Gough D, Cain JE, Firestein R. Sun CX, et al. Among authors: rosenbluh j. Cancer Cell. 2023 Apr 10;41(4):660-677.e7. doi: 10.1016/j.ccell.2023.03.007. Epub 2023 Mar 30. Cancer Cell. 2023. PMID: 37001527 Free article.
Pediatric glioma histone H3.3 K27M/G34R mutations drive abnormalities in PML nuclear bodies.
Voon HPJ, Hii L, Garvie A, Udugama M, Krug B, Russo C, Chüeh AC, Daly RJ, Morey A, Bell TDM, Turner SJ, Rosenbluh J, Daniel P, Firestein R, Mann JR, Collas P, Jabado N, Wong LH. Voon HPJ, et al. Among authors: rosenbluh j. Genome Biol. 2023 Dec 8;24(1):284. doi: 10.1186/s13059-023-03122-5. Genome Biol. 2023. PMID: 38066546 Free PMC article.
Heritable methylation marks associated with prostate cancer risk.
Dowty JG, Yu C, Hosseinpour M, Joo JE, Wong EM, Nguyen-Dumont T, Rosenbluh J, Giles GG, Milne RL, MacInnis RJ, Dugué PA, Southey MC. Dowty JG, et al. Among authors: rosenbluh j. Fam Cancer. 2023 Jul;22(3):313-317. doi: 10.1007/s10689-022-00325-w. Epub 2023 Jan 28. Fam Cancer. 2023. PMID: 36708485 Free PMC article.
SAM-DNMT3A, a strategy for induction of genome-wide DNA methylation, identifies DNA methylation as a vulnerability in ER-positive breast cancers.
Hosseinpour M, Xi X, Liu L, Malaver-Ortega L, Perlaza-Jimenez L, Joo JE, York HM, Beesley J, Caldon CE, Dugué PA, Dowty JG, Arumugam S, Southey MC, Rosenbluh J. Hosseinpour M, et al. Among authors: rosenbluh j. Nat Commun. 2024 Dec 1;15(1):10449. doi: 10.1038/s41467-024-54824-8. Nat Commun. 2024. PMID: 39617792 Free PMC article.
CRISPR screens identify gene targets at breast cancer risk loci.
Tuano NK, Beesley J, Manning M, Shi W, Perlaza-Jimenez L, Malaver-Ortega LF, Paynter JM, Black D, Civitarese A, McCue K, Hatzipantelis A, Hillman K, Kaufmann S, Sivakumaran H, Polo JM, Reddel RR, Band V, French JD, Edwards SL, Powell DR, Chenevix-Trench G, Rosenbluh J. Tuano NK, et al. Among authors: rosenbluh j. Genome Biol. 2023 Mar 29;24(1):59. doi: 10.1186/s13059-023-02898-w. Genome Biol. 2023. PMID: 36991492 Free PMC article.
46 results