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Caspase-1 independent IL-1beta production is critical for host resistance to mycobacterium tuberculosis and does not require TLR signaling in vivo.
Mayer-Barber KD, Barber DL, Shenderov K, White SD, Wilson MS, Cheever A, Kugler D, Hieny S, Caspar P, Núñez G, Schlueter D, Flavell RA, Sutterwala FS, Sher A. Mayer-Barber KD, et al. J Immunol. 2010 Apr 1;184(7):3326-30. doi: 10.4049/jimmunol.0904189. Epub 2010 Mar 3. J Immunol. 2010. PMID: 20200276 Free PMC article.
Role of innate cytokines in mycobacterial infection.
Cooper AM, Mayer-Barber KD, Sher A. Cooper AM, et al. Mucosal Immunol. 2011 May;4(3):252-60. doi: 10.1038/mi.2011.13. Epub 2011 Mar 23. Mucosal Immunol. 2011. PMID: 21430655 Free PMC article. Review.
Cord factor and peptidoglycan recapitulate the Th17-promoting adjuvant activity of mycobacteria through mincle/CARD9 signaling and the inflammasome.
Shenderov K, Barber DL, Mayer-Barber KD, Gurcha SS, Jankovic D, Feng CG, Oland S, Hieny S, Caspar P, Yamasaki S, Lin X, Ting JP, Trinchieri G, Besra GS, Cerundolo V, Sher A. Shenderov K, et al. J Immunol. 2013 Jun 1;190(11):5722-30. doi: 10.4049/jimmunol.1203343. Epub 2013 Apr 29. J Immunol. 2013. PMID: 23630357 Free PMC article.
78 results