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A Living Organoid Biobank of Crohn's Disease Patients Reveals Molecular Subtypes for Personalized Therapeutics.
Tindle C, Katkar GD, Fonseca AG, Taheri S, Lee J, Maity P, Sayed IM, Ibeawuchi SR, Vidales E, Pranadinata RF, Fuller M, Stec DL, Anandachar MS, Perry K, Le HN, Ear J, Boland BS, Sandborn WJ, Sahoo D, Das S, Ghosh P. Tindle C, et al. Among authors: das s. bioRxiv [Preprint]. 2023 Mar 13:2023.03.11.532245. doi: 10.1101/2023.03.11.532245. bioRxiv. 2023. Update in: Cell Rep Med. 2024 Oct 15;5(10):101748. doi: 10.1016/j.xcrm.2024.101748 PMID: 36993763 Free PMC article. Updated. Preprint.
Anticancer pan-ErbB inhibitors reduce inflammation and tissue injury and exert broad-spectrum antiviral effects.
Saul S, Karim M, Ghita L, Huang PT, Chiu W, Durán V, Lo CW, Kumar S, Bhalla N, Leyssen P, Alem F, Boghdeh NA, Tran DH, Cohen CA, Brown JA, Huie KE, Tindle C, Sibai M, Ye C, Khalil AM, Martinez-Sobrido L, Dye JM, Pinsky BA, Ghosh P, Das S, Solow-Cordero DE, Jin J, Wikswo JP, Jochmans D, Neyts J, Jonghe S, Narayanan A, Einav S. Saul S, et al. Among authors: das s. bioRxiv [Preprint]. 2023 May 10:2021.05.15.444128. doi: 10.1101/2021.05.15.444128. bioRxiv. 2023. Update in: J Clin Invest. 2023 Oct 2;133(19):e169510. doi: 10.1172/JCI169510 PMID: 34159337 Free PMC article. Updated. Preprint.
PIP4K2C inhibition reverses autophagic flux impairment induced by SARS-CoV-2.
Karim M, Mishra M, Lo CW, Saul S, Cagirici HB, Tran DHN, Agrawal A, Ghita L, Ojha A, East MP, Gammeltoft KA, Sahoo MK, Johnson GL, Das S, Jochmans D, Cohen CA, Gottwein J, Dye J, Neff N, Pinsky BA, Laitinen T, Pantsar T, Poso A, Zanini F, Jonghe S, Asquith CRM, Einav S. Karim M, et al. Among authors: das s. bioRxiv [Preprint]. 2024 Apr 17:2024.04.15.589676. doi: 10.1101/2024.04.15.589676. bioRxiv. 2024. PMID: 38659941 Free PMC article. Preprint.
Simultaneous Unbinned Differential Cross-Section Measurement of Twenty-Four Z+jets Kinematic Observables with the ATLAS Detector.
Aad G, Aakvaag E, Abbott B, Abdelhameed S, Abeling K, Abicht NJ, Abidi SH, Aboelela M, Aboulhorma A, Abramowicz H, Abreu H, Abulaiti Y, Acharya BS, Ackermann A, Adam Bourdarios C, Adamczyk L, Addepalli SV, Addison MJ, Adelman J, Adiguzel A, Adye T, Affolder AA, Afik Y, Agaras MN, Agarwala J, Aggarwal A, Agheorghiesei C, Ahmadov F, Ahmed WS, Ahuja S, Ai X, Aielli G, Aikot A, Ait Tamlihat M, Aitbenchikh B, Akbiyik M, Åkesson TPA, Akimov AV, Akiyama D, Akolkar NN, Aktas S, Al Khoury K, Alberghi GL, Albert J, Albicocco P, Albouy GL, Alderweireldt S, Alegria ZL, Aleksa M, Aleksandrov IN, Alexa C, Alexopoulos T, Alfonsi F, Algren M, Alhroob M, Ali B, Ali HMJ, Ali S, Alibocus SW, Aliev M, Alimonti G, Alkakhi W, Allaire C, Allbrooke BMM, Allen JF, Allendes Flores CA, Allport PP, Aloisio A, Alonso F, Alpigiani C, Alsolami ZMK, Alvarez Estevez M, Alvarez Fernandez A, Alves Cardoso M, Alviggi MG, Aly M, Amaral Coutinho Y, Ambler A, Amelung C, Amerl M, Ames CG, Amidei D, Amirie KJ, Amor Dos Santos SP, Amos KR, An S, Ananiev V, Anastopoulos C, Andeen T, Anders JK, Anderson AC, Andrean SY, Andreazza A, Angelidakis S, Angerami A, Anisenkov AV, Annovi A, Antel C, Antipov E, Antonelli M, Anulli F,… See abstract for full author list ➔ Aad G, et al. Among authors: das sj. Phys Rev Lett. 2024 Dec 31;133(26):261803. doi: 10.1103/PhysRevLett.133.261803. Phys Rev Lett. 2024. PMID: 39878999
A multi-cohort study of longitudinal and cross-sectional Alzheimer's disease biomarkers in cognitively unimpaired older adults.
Xie L, Das SR, Li Y, Wisse LEM, McGrew E, Lyu X, DiCalogero M, Shah U, Ilesanmi A, Denning AE, Brown CA, Cohen J, Sreepada L, Dong M, Sadeghpour N, Khandelwal P, Ittyerah R, Ravikumar S, Sadaghiani S, Hrybouski S, de Flores R, Gibson E, Yushkevich PA, Wolk DA; Alzheimer's Disease Neuroimaging Initiative. Xie L, et al. Among authors: das sr. Alzheimers Dement. 2025 Jan 27. doi: 10.1002/alz.14492. Online ahead of print. Alzheimers Dement. 2025. PMID: 39868491
Loss of Parp7 increases type I interferon signalling and reduces pancreatic tumour growth by enhancing immune cell infiltration.
Kannen V, Rasmussen M, Das S, Giuliana P, Izzati FN, Choksi H, Erlingsson LAM, Olafsen NE, Åhrling SS, Cappello P, Teino I, Maimets T, Jaudzems K, Gulbinas A, Dambrauskas Z, Edgar LJ, Grant DM, Matthews J. Kannen V, et al. Among authors: das s. Front Immunol. 2025 Jan 10;15:1513595. doi: 10.3389/fimmu.2024.1513595. eCollection 2024. Front Immunol. 2025. PMID: 39867896 Free PMC article.
Tau Burden is Best Captured by Magnitude and Extent: Tau-MaX as a Measure of Global Tau.
Brown CA, Das SR, Cousins KAQ, Tropea TF, Plotkin AC, Detre JA, Yushkevich PA, McMillan CT, Lee EB, Shaw LM, Nasrallah IM; Alzheimer’s Disease Neuroimaging Initiative; Wolk DA. Brown CA, et al. Among authors: das sr. medRxiv [Preprint]. 2025 Jan 14:2025.01.13.25320488. doi: 10.1101/2025.01.13.25320488. medRxiv. 2025. PMID: 39867392 Free PMC article. Preprint.
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