Lee SY - Search Results

1

Molecular basis of polyspecific drug binding and transport by OCT1 and OCT2.

Suo Y, Wright NJ, Guterres H, Fedor JG, Butay KJ, Borgnia MJ, Im W, Lee SY. Suo Y, et al. Among authors: lee sy. bioRxiv [Preprint]. 2023 Mar 16:2023.03.15.532610. doi: 10.1101/2023.03.15.532610. bioRxiv. 2023. Update in: Nat Struct Mol Biol. 2023 Jul;30(7):1001-1011. doi: 10.1038/s41594-023-01017-4 PMID: 36993738 Free PMC article. Updated. Preprint.

2

Cryo-electron microscopy structure of the lysosomal calcium-permeable channel TRPML3.

Hirschi M, Herzik MA Jr, Wie J, Suo Y, Borschel WF, Ren D, Lander GC, Lee SY. Hirschi M, et al. Among authors: lee sy. Nature. 2017 Oct 19;550(7676):411-414. doi: 10.1038/nature24055. Epub 2017 Oct 11. Nature. 2017. PMID: 29019979 Free PMC article.

3

Structural basis of cooling agent and lipid sensing by the cold-activated TRPM8 channel.

Yin Y, Le SC, Hsu AL, Borgnia MJ, Yang H, Lee SY. Yin Y, et al. Among authors: lee sy. Science. 2019 Mar 1;363(6430):eaav9334. doi: 10.1126/science.aav9334. Epub 2019 Feb 7. Science. 2019. PMID: 30733385 Free PMC article.

4

Regulatory switch at the cytoplasmic interface controls TRPV channel gating.

Zubcevic L, Borschel WF, Hsu AL, Borgnia MJ, Lee SY. Zubcevic L, et al. Among authors: lee sy. Elife. 2019 May 9;8:e47746. doi: 10.7554/eLife.47746. Elife. 2019. PMID: 31070581 Free PMC article.

5

Symmetry transitions during gating of the TRPV2 ion channel in lipid membranes.

Zubcevic L, Hsu AL, Borgnia MJ, Lee SY. Zubcevic L, et al. Among authors: lee sy. Elife. 2019 May 15;8:e45779. doi: 10.7554/eLife.45779. Elife. 2019. PMID: 31090543 Free PMC article.

6

Structures of human ENT1 in complex with adenosine reuptake inhibitors.

Wright NJ, Lee SY. Wright NJ, et al. Among authors: lee sy. Nat Struct Mol Biol. 2019 Jul;26(7):599-606. doi: 10.1038/s41594-019-0245-7. Epub 2019 Jun 24. Nat Struct Mol Biol. 2019. PMID: 31235912 Free PMC article.

7

Visualizing structural transitions of ligand-dependent gating of the TRPM2 channel.

Yin Y, Wu M, Hsu AL, Borschel WF, Borgnia MJ, Lander GC, Lee SY. Yin Y, et al. Among authors: lee sy. Nat Commun. 2019 Aug 20;10(1):3740. doi: 10.1038/s41467-019-11733-5. Nat Commun. 2019. PMID: 31431622 Free PMC article.

8

Structural Insights into Electrophile Irritant Sensing by the Human TRPA1 Channel.

Suo Y, Wang Z, Zubcevic L, Hsu AL, He Q, Borgnia MJ, Ji RR, Lee SY. Suo Y, et al. Among authors: lee sy. Neuron. 2020 Mar 4;105(5):882-894.e5. doi: 10.1016/j.neuron.2019.11.023. Epub 2019 Dec 19. Neuron. 2020. PMID: 31866091 Free PMC article.

9

Toward a Molecular Basis of Cellular Nucleoside Transport in Humans.

Wright NJ, Lee SY. Wright NJ, et al. Among authors: lee sy. Chem Rev. 2021 May 12;121(9):5336-5358. doi: 10.1021/acs.chemrev.0c00644. Epub 2020 Nov 24. Chem Rev. 2021. PMID: 33232132 Free PMC article. Review.

10

Sample preparation of the human TRPA1 ion channel for cryo-EM studies.

Suo Y, Lee SY. Suo Y, et al. Among authors: lee sy. Methods Enzymol. 2021;653:75-87. doi: 10.1016/bs.mie.2020.12.018. Epub 2021 Jan 27. Methods Enzymol. 2021. PMID: 34099182 Free PMC article.

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