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AlphaFold2 enables accurate deorphanization of ligands to single-pass receptors.
Danneskiold-Samsøe NB, Kavi D, Jude KM, Nissen SB, Wat LW, Coassolo L, Zhao M, Santana-Oikawa GA, Broido BB, Garcia KC, Svensson KJ. Danneskiold-Samsøe NB, et al. Among authors: zhao m. bioRxiv [Preprint]. 2023 Dec 15:2023.03.16.531341. doi: 10.1101/2023.03.16.531341. bioRxiv. 2023. Update in: Cell Syst. 2024 Nov 20;15(11):1046-1060.e3. doi: 10.1016/j.cels.2024.10.004 PMID: 36993313 Free PMC article. Updated. Preprint.
Mitochondrial uncoupler and retinoic acid synergistically induce differentiation and inhibit proliferation in neuroblastoma.
Jiang H, Tiche SJ, He CJ, Jedoui M, Forgo B, Zhao M, He B, Li Y, Li AM, Truong AT, Ho J, Simmermaker C, Yang Y, Zhou MN, Hu Z, Cuthbertson DJ, Svensson KJ, Hazard FK, Shimada H, Chiu B, Ye J. Jiang H, et al. Among authors: zhao m. bioRxiv [Preprint]. 2024 Jan 25:2024.01.22.576741. doi: 10.1101/2024.01.22.576741. bioRxiv. 2024. PMID: 38328117 Free PMC article. Preprint.
A PTER-dependent pathway of taurine metabolism linked to energy balance.
Wei W, Lyu X, Markhard AL, Fu S, Mardjuki RE, Cavanagh PE, Zeng X, Rajniak J, Lu N, Xiao S, Zhao M, Moya-Garzon MD, Truong SD, Chou JC, Wat LW, Chidambaranathan-Reghupaty S, Coassolo L, Xu D, Shen F, Huang W, Ramirez CB, Jang C, Svensson KJ, Fischbach MA, Long JZ. Wei W, et al. Among authors: zhao m. bioRxiv [Preprint]. 2024 Mar 22:2024.03.21.586194. doi: 10.1101/2024.03.21.586194. bioRxiv. 2024. PMID: 38562797 Free PMC article. Preprint.
PTER is a N-acetyltaurine hydrolase that regulates feeding and obesity.
Wei W, Lyu X, Markhard AL, Fu S, Mardjuki RE, Cavanagh PE, Zeng X, Rajniak J, Lu N, Xiao S, Zhao M, Moya-Garzon MD, Truong SD, Chou JC, Wat LW, Chidambaranathan-Reghupaty S, Coassolo L, Xu D, Shen F, Huang W, Ramirez CB, Jang C, Li L, Svensson KJ, Fischbach MA, Long JZ. Wei W, et al. Among authors: zhao m. Nature. 2024 Sep;633(8028):182-188. doi: 10.1038/s41586-024-07801-6. Epub 2024 Aug 7. Nature. 2024. PMID: 39112712 Free PMC article.
Loss of RREB1 reduces adipogenesis and improves insulin sensitivity in mouse and human adipocytes.
Yu GZ, Krentz NAJ, Bentley L, Zhao M, Paphiti K, Sun H, Honecker J, Nygård M, Dashti H, Bai Y, Reid M, Thaman S, Wabitsch M, Rajesh V, Yang J, Mattis KK, Abaitua F, Casero R, Hauner H, Knowles JW, Wu JY, Mandrup S, Claussnitzer M, Svensson KJ, Cox RD, Gloyn AL. Yu GZ, et al. Among authors: zhao m. bioRxiv [Preprint]. 2024 Jul 31:2024.07.30.605923. doi: 10.1101/2024.07.30.605923. bioRxiv. 2024. PMID: 39131393 Free PMC article. Preprint.
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