Schiffer CA - Search Results

1

Crystal Structures of Inhibitor-Bound Main Protease from Delta- and Gamma-Coronaviruses.

Zvornicanin SN, Shaqra AM, Huang QJ, Ornelas E, Moghe M, Knapp M, Moquin S, Dovala D, Schiffer CA, Kurt Yilmaz N. Zvornicanin SN, et al. Among authors: schiffer ca. Viruses. 2023 Mar 18;15(3):781. doi: 10.3390/v15030781. Viruses. 2023. PMID: 36992489 Free PMC article.

2

Molecular Basis for Drug Resistance in HIV-1 Protease.

Ali A, Bandaranayake RM, Cai Y, King NM, Kolli M, Mittal S, Murzycki JF, Nalam MNL, Nalivaika EA, Özen A, Prabu-Jeyabalan MM, Thayer K, Schiffer CA. Ali A, et al. Among authors: schiffer ca. Viruses. 2010 Nov;2(11):2509-2535. doi: 10.3390/v2112509. Epub 2010 Nov 12. Viruses. 2010. PMID: 21994628 Free PMC article.

3

Cooperative effects of drug-resistance mutations in the flap region of HIV-1 protease.

Foulkes-Murzycki JE, Rosi C, Kurt Yilmaz N, Shafer RW, Schiffer CA. Foulkes-Murzycki JE, et al. Among authors: schiffer ca. ACS Chem Biol. 2013 Mar 15;8(3):513-8. doi: 10.1021/cb3006193. Epub 2012 Dec 27. ACS Chem Biol. 2013. PMID: 23252515 Free PMC article.

4

HIV-1 protease-substrate coevolution in nelfinavir resistance.

Kolli M, Ozen A, Kurt-Yilmaz N, Schiffer CA. Kolli M, et al. Among authors: schiffer ca. J Virol. 2014 Jul;88(13):7145-54. doi: 10.1128/JVI.00266-14. Epub 2014 Apr 9. J Virol. 2014. PMID: 24719428 Free PMC article.

5

Drug resistance conferred by mutations outside the active site through alterations in the dynamic and structural ensemble of HIV-1 protease.

Ragland DA, Nalivaika EA, Nalam MN, Prachanronarong KL, Cao H, Bandaranayake RM, Cai Y, Kurt-Yilmaz N, Schiffer CA. Ragland DA, et al. Among authors: schiffer ca. J Am Chem Soc. 2014 Aug 27;136(34):11956-63. doi: 10.1021/ja504096m. Epub 2014 Aug 18. J Am Chem Soc. 2014. PMID: 25091085 Free PMC article.

6

Drug Resistance Mutations Alter Dynamics of Inhibitor-Bound HIV-1 Protease.

Cai Y, Myint W, Paulsen JL, Schiffer CA, Ishima R, Kurt Yilmaz N. Cai Y, et al. Among authors: schiffer ca. J Chem Theory Comput. 2014 Aug 12;10(8):3438-3448. doi: 10.1021/ct4010454. Epub 2014 Jun 12. J Chem Theory Comput. 2014. PMID: 25136270 Free PMC article.

7

Structural basis and distal effects of Gag substrate coevolution in drug resistance to HIV-1 protease.

Özen A, Lin KH, Kurt Yilmaz N, Schiffer CA. Özen A, et al. Among authors: schiffer ca. Proc Natl Acad Sci U S A. 2014 Nov 11;111(45):15993-8. doi: 10.1073/pnas.1414063111. Epub 2014 Oct 29. Proc Natl Acad Sci U S A. 2014. PMID: 25355911 Free PMC article.

8

The ssDNA Mutator APOBEC3A Is Regulated by Cooperative Dimerization.

Bohn MF, Shandilya SMD, Silvas TV, Nalivaika EA, Kouno T, Kelch BA, Ryder SP, Kurt-Yilmaz N, Somasundaran M, Schiffer CA. Bohn MF, et al. Among authors: schiffer ca. Structure. 2015 May 5;23(5):903-911. doi: 10.1016/j.str.2015.03.016. Epub 2015 Apr 23. Structure. 2015. PMID: 25914058 Free PMC article.

9

Structural and Thermodynamic Effects of Macrocyclization in HCV NS3/4A Inhibitor MK-5172.

Soumana DI, Kurt Yilmaz N, Prachanronarong KL, Aydin C, Ali A, Schiffer CA. Soumana DI, et al. Among authors: schiffer ca. ACS Chem Biol. 2016 Apr 15;11(4):900-9. doi: 10.1021/acschembio.5b00647. Epub 2016 Jan 6. ACS Chem Biol. 2016. PMID: 26682473 Free PMC article.

10

Improving Viral Protease Inhibitors to Counter Drug Resistance.

Kurt Yilmaz N, Swanstrom R, Schiffer CA. Kurt Yilmaz N, et al. Among authors: schiffer ca. Trends Microbiol. 2016 Jul;24(7):547-557. doi: 10.1016/j.tim.2016.03.010. Epub 2016 Apr 15. Trends Microbiol. 2016. PMID: 27090931 Free PMC article. Review.

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