Kurt Yilmaz N - Search Results

1

Direct delivery of Cas-embedded cytosine base editors as ribonucleoprotein complexes for efficient and accurate editing of clinically relevant targets.

Lee JM, Zeng J, Liu P, Nguyen MA, Suchenski Loustaunau D, Bauer DE, Kurt Yilmaz N, Wolfe SA, Schiffer CA. Lee JM, et al. Among authors: kurt yilmaz n. Nucleic Acids Res. 2024 Dec 16:gkae1217. doi: 10.1093/nar/gkae1217. Online ahead of print. Nucleic Acids Res. 2024. PMID: 39676659

2

Elucidating the Substrate Envelope of Enterovirus 68-3C Protease: Structural Basis of Specificity and Potential Resistance.

Azzolino VN, Shaqra AM, Ali A, Kurt Yilmaz N, Schiffer CA. Azzolino VN, et al. Among authors: kurt yilmaz n. Viruses. 2024 Sep 5;16(9):1419. doi: 10.3390/v16091419. Viruses. 2024. PMID: 39339895 Free PMC article.

3

Next generation APOBEC3 inhibitors: Optimally designed for potency and nuclease stability.

Hedger AK, Myint W, Lee JM, Suchenski-Loustaunau D, Balachandran V, Shaqra AM, Kurt-Yilmaz N, Watts JK, Matsuo H, Schiffer CA. Hedger AK, et al. Among authors: kurt yilmaz n. bioRxiv [Preprint]. 2024 Sep 6:2024.09.05.611238. doi: 10.1101/2024.09.05.611238. bioRxiv. 2024. PMID: 39282427 Free PMC article. Preprint.

4

Contributions of Hyperactive Mutations in M^pro from SARS-CoV-2 to Drug Resistance.

Flynn JM, Zvornicanin SN, Tsepal T, Shaqra AM, Kurt Yilmaz N, Jia W, Moquin S, Dovala D, Schiffer CA, Bolon DNA. Flynn JM, et al. Among authors: kurt yilmaz n. ACS Infect Dis. 2024 Apr 12;10(4):1174-1184. doi: 10.1021/acsinfecdis.3c00560. Epub 2024 Mar 12. ACS Infect Dis. 2024. PMID: 38472113

5

Crystal Structures of Inhibitor-Bound Main Protease from Delta- and Gamma-Coronaviruses.

Zvornicanin SN, Shaqra AM, Huang QJ, Ornelas E, Moghe M, Knapp M, Moquin S, Dovala D, Schiffer CA, Kurt Yilmaz N. Zvornicanin SN, et al. Among authors: kurt yilmaz n. Viruses. 2023 Mar 18;15(3):781. doi: 10.3390/v15030781. Viruses. 2023. PMID: 36992489 Free PMC article.

6

Allosteric quinoxaline-based inhibitors of the flavivirus NS2B/NS3 protease.

Zephyr J, Rao DN, Johnson C, Shaqra AM, Nalivaika EA, Jordan A, Kurt Yilmaz N, Ali A, Schiffer CA. Zephyr J, et al. Among authors: kurt yilmaz n. Bioorg Chem. 2023 Feb;131:106269. doi: 10.1016/j.bioorg.2022.106269. Epub 2022 Nov 19. Bioorg Chem. 2023. PMID: 36446201 Free PMC article.

7

Defining the substrate envelope of SARS-CoV-2 main protease to predict and avoid drug resistance.

Shaqra AM, Zvornicanin SN, Huang QYJ, Lockbaum GJ, Knapp M, Tandeske L, Bakan DT, Flynn J, Bolon DNA, Moquin S, Dovala D, Kurt Yilmaz N, Schiffer CA. Shaqra AM, et al. Among authors: kurt yilmaz n. Nat Commun. 2022 Jun 21;13(1):3556. doi: 10.1038/s41467-022-31210-w. Nat Commun. 2022. PMID: 35729165 Free PMC article.

8

Deciphering the Molecular Mechanism of HCV Protease Inhibitor Fluorination as a General Approach to Avoid Drug Resistance.

Zephyr J, Nageswara Rao D, Vo SV, Henes M, Kosovrasti K, Matthew AN, Hedger AK, Timm J, Chan ET, Ali A, Kurt Yilmaz N, Schiffer CA. Zephyr J, et al. Among authors: kurt yilmaz n. J Mol Biol. 2022 May 15;434(9):167503. doi: 10.1016/j.jmb.2022.167503. Epub 2022 Feb 17. J Mol Biol. 2022. PMID: 35183560 Free PMC article.

9

Viral proteases: Structure, mechanism and inhibition.

Zephyr J, Kurt Yilmaz N, Schiffer CA. Zephyr J, et al. Among authors: kurt yilmaz n. Enzymes. 2021;50:301-333. doi: 10.1016/bs.enz.2021.09.004. Epub 2021 Nov 17. Enzymes. 2021. PMID: 34861941 Free PMC article.

10

Pan-3C Protease Inhibitor Rupintrivir Binds SARS-CoV-2 Main Protease in a Unique Binding Mode.

Lockbaum GJ, Henes M, Lee JM, Timm J, Nalivaika EA, Thompson PR, Kurt Yilmaz N, Schiffer CA. Lockbaum GJ, et al. Among authors: kurt yilmaz n. Biochemistry. 2021 Oct 5;60(39):2925-2931. doi: 10.1021/acs.biochem.1c00414. Epub 2021 Sep 10. Biochemistry. 2021. PMID: 34506130 Free PMC article.

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