Liu Y - Search Results

1

Design, synthesis and pharmacological characterization of aminopyrimidine derivatives as BTK/FLT3 dual-target inhibitors against acute myeloid leukemia.

Ran F, Liu Y, Zhu J, Deng X, Wu H, Tao W, Xie X, Hu Y, Zhang Y, Ling Y. Ran F, et al. Among authors: liu y. Bioorg Chem. 2023 May;134:106479. doi: 10.1016/j.bioorg.2023.106479. Epub 2023 Mar 13. Bioorg Chem. 2023. PMID: 36989958

2

Development of novel hydrazidoarylaminopyrimidine-based BTK/FLT3 dual inhibitors with potent in vivo anti-hematological malignancies effects.

Ran F, Xie X, Wu Q, Wu H, Liu Y, Tao W, Sun Y, Wang R, Zhang Y, Ling Y. Ran F, et al. Among authors: liu y. Eur J Med Chem. 2023 Jan 5;245(Pt 1):114913. doi: 10.1016/j.ejmech.2022.114913. Epub 2022 Nov 10. Eur J Med Chem. 2023. PMID: 36399923

3

1,3-Substituted β-Carboline Derivatives as Potent Chemotherapy for the Treatment of Cystic Echinococcosis.

Chen B, Wu J, Yan Z, Wu H, Gao H, Liu Y, Zhao J, Wang J, Yang J, Zhang Y, Pan J, Ling Y, Wen H, Huang Z. Chen B, et al. Among authors: liu y. J Med Chem. 2023 Dec 28;66(24):16680-16693. doi: 10.1021/acs.jmedchem.3c01326. Epub 2023 Dec 9. J Med Chem. 2023. PMID: 38069814

4

Discovery, Synthesis, and Evaluation of Novel Dual Inhibitors of a Vascular Endothelial Growth Factor Receptor and Poly(ADP-Ribose) Polymerase for BRCA Wild-Type Breast Cancer Therapy.

Li Y, Liu Y, Zhang D, Chen J, Yang G, Tang P, Yang C, Liu J, Zhang J, Ouyang L. Li Y, et al. Among authors: liu j, liu y. J Med Chem. 2023 Sep 14;66(17):12069-12100. doi: 10.1021/acs.jmedchem.3c00640. Epub 2023 Aug 24. J Med Chem. 2023. PMID: 37616488

5

The YAP-TEAD4 complex promotes tumor lymphangiogenesis by transcriptionally upregulating CCBE1 in colorectal cancer.

Song J, Dang X, Shen X, Liu Y, Gu J, Peng X, Huang Z, Hong W, Cui L, Liu CY. Song J, et al. Among authors: liu y, liu cy. J Biol Chem. 2023 Apr;299(4):103012. doi: 10.1016/j.jbc.2023.103012. Epub 2023 Feb 11. J Biol Chem. 2023. PMID: 36781122 Free PMC article.

6

Dual-targeting of tumor cells and tumor-associated macrophages by hyaluronic acid-modified MnO₂ for enhanced sonodynamic therapy.

Liu Y, Zhang Z, Xia Y, Ran M, Wang Q, Wu Q, Yu W, Li C, Li S, Guo N. Liu Y, et al. Int J Biol Macromol. 2024 Dec;283(Pt 1):137543. doi: 10.1016/j.ijbiomac.2024.137543. Epub 2024 Nov 13. Int J Biol Macromol. 2024. PMID: 39542302

7

Recent progress on vascular endothelial growth factor receptor inhibitors with dual targeting capabilities for tumor therapy.

Liu Y, Li Y, Wang Y, Lin C, Zhang D, Chen J, Ouyang L, Wu F, Zhang J, Chen L. Liu Y, et al. J Hematol Oncol. 2022 Jul 7;15(1):89. doi: 10.1186/s13045-022-01310-7. J Hematol Oncol. 2022. PMID: 35799213 Free PMC article. Review.

8

Discovery of 4-Hydroxyquinazoline Derivatives as Small Molecular BET/PARP1 Inhibitors That Induce Defective Homologous Recombination and Lead to Synthetic Lethality for Triple-Negative Breast Cancer Therapy.

Zhang J, Yang C, Tang P, Chen J, Zhang D, Li Y, Yang G, Liu Y, Zhang Y, Wang Y, Liu J, Ouyang L. Zhang J, et al. Among authors: liu j, liu y. J Med Chem. 2022 May 12;65(9):6803-6825. doi: 10.1021/acs.jmedchem.2c00135. Epub 2022 Apr 20. J Med Chem. 2022. PMID: 35442700

9

Novel Medicinal Chemistry Strategies Targeting CDK5 for Drug Discovery.

Tang W, Lin C, Yu Q, Zhang D, Liu Y, Zhang L, Zhou Z, Zhang J, Ouyang L. Tang W, et al. Among authors: liu y. J Med Chem. 2023 Jun 8;66(11):7140-7161. doi: 10.1021/acs.jmedchem.3c00566. Epub 2023 May 26. J Med Chem. 2023. PMID: 37234044 Review.

10

Diversity-oriented synthesis of diterpenoid alkaloids yields a potent anti-inflammatory agent.

Li X, Zhang J, Chen Q, Tang P, Zhang T, Feng Q, Chen J, Liu Y, Wang FP, Peng C, Qin Y, Ouyang L, Xiao K, Liu XY. Li X, et al. Among authors: liu xy, liu y. Phytomedicine. 2023 Aug;117:154907. doi: 10.1016/j.phymed.2023.154907. Epub 2023 May 29. Phytomedicine. 2023. PMID: 37295024

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