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Page 1
Calmodulin-dependent kinase II mediates vascular smooth muscle cell proliferation and is potentiated by extracellular signal regulated kinase.
Cipolletta E, Monaco S, Maione AS, Vitiello L, Campiglia P, Pastore L, Franchini C, Novellino E, Limongelli V, Bayer KU, Means AR, Rossi G, Trimarco B, Iaccarino G, Illario M. Cipolletta E, et al. Among authors: limongelli v. Endocrinology. 2010 Jun;151(6):2747-59. doi: 10.1210/en.2009-1248. Epub 2010 Apr 14. Endocrinology. 2010. PMID: 20392834 Free PMC article.
New insight into the central benzodiazepine receptor-ligand interactions: design, synthesis, biological evaluation, and molecular modeling of 3-substituted 6-phenyl-4H-imidazo[1,5-a][1,4]benzodiazepines and related compounds.
Anzini M, Valenti S, Braile C, Cappelli A, Vomero S, Alcaro S, Ortuso F, Marinelli L, Limongelli V, Novellino E, Betti L, Giannaccini G, Lucacchini A, Daniele S, Martini C, Ghelardini C, Di Cesare Mannelli L, Giorgi G, Mascia MP, Biggio G. Anzini M, et al. Among authors: limongelli v. J Med Chem. 2011 Aug 25;54(16):5694-711. doi: 10.1021/jm2001597. Epub 2011 Jul 27. J Med Chem. 2011. PMID: 21751815
Potent arylsulfonamide inhibitors of tumor necrosis factor-alpha converting enzyme able to reduce activated leukocyte cell adhesion molecule shedding in cancer cell models.
Nuti E, Casalini F, Avramova SI, Santamaria S, Fabbi M, Ferrini S, Marinelli L, La Pietra V, Limongelli V, Novellino E, Cercignani G, Orlandini E, Nencetti S, Rossello A. Nuti E, et al. Among authors: limongelli v. J Med Chem. 2010 Mar 25;53(6):2622-35. doi: 10.1021/jm901868z. J Med Chem. 2010. PMID: 20180536
Design, synthesis, and biological evaluation of novel aminobisphosphonates possessing an in vivo antitumor activity through a gammadelta-T lymphocytes-mediated activation mechanism.
Simoni D, Gebbia N, Invidiata FP, Eleopra M, Marchetti P, Rondanin R, Baruchello R, Provera S, Marchioro C, Tolomeo M, Marinelli L, Limongelli V, Novellino E, Kwaasi A, Dunford J, Buccheri S, Caccamo N, Dieli F. Simoni D, et al. Among authors: limongelli v. J Med Chem. 2008 Nov 13;51(21):6800-7. doi: 10.1021/jm801003y. Epub 2008 Oct 21. J Med Chem. 2008. PMID: 18937434
Ethyl 8-fluoro-6-(3-nitrophenyl)-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate as novel, highly potent, and safe antianxiety agent.
Anzini M, Braile C, Valenti S, Cappelli A, Vomero S, Marinelli L, Limongelli V, Novellino E, Betti L, Giannaccini G, Lucacchini A, Ghelardini C, Norcini M, Makovec F, Giorgi G, Ian Fryer R. Anzini M, et al. Among authors: limongelli v. J Med Chem. 2008 Aug 14;51(15):4730-43. doi: 10.1021/jm8002944. Epub 2008 Jul 19. J Med Chem. 2008. PMID: 18637672
Binding mechanism of the farnesoid X receptor marine antagonist suvanine reveals a strategy to forestall drug modulation on nuclear receptors. Design, synthesis, and biological evaluation of novel ligands.
Di Leva FS, Festa C, D'Amore C, De Marino S, Renga B, D'Auria MV, Novellino E, Limongelli V, Zampella A, Fiorucci S. Di Leva FS, et al. Among authors: limongelli v. J Med Chem. 2013 Jun 13;56(11):4701-17. doi: 10.1021/jm400419e. Epub 2013 May 24. J Med Chem. 2013. PMID: 23656455
79 results