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Total Chemical Synthesis of LC3A and LC3B Activity-Based Probes.
Huppelschoten Y, Buchardt J, Nielsen TE, Sapmaz A, van der Heden van Noort GJ. Huppelschoten Y, et al. Among authors: van der heden van noort gj. Biomedicines. 2023 Mar 13;11(3):884. doi: 10.3390/biomedicines11030884. Biomedicines. 2023. PMID: 36979862 Free PMC article.
Papain-like protease regulates SARS-CoV-2 viral spread and innate immunity.
Shin D, Mukherjee R, Grewe D, Bojkova D, Baek K, Bhattacharya A, Schulz L, Widera M, Mehdipour AR, Tascher G, Geurink PP, Wilhelm A, van der Heden van Noort GJ, Ovaa H, Müller S, Knobeloch KP, Rajalingam K, Schulman BA, Cinatl J, Hummer G, Ciesek S, Dikic I. Shin D, et al. Among authors: van der heden van noort gj. Nature. 2020 Nov;587(7835):657-662. doi: 10.1038/s41586-020-2601-5. Epub 2020 Jul 29. Nature. 2020. PMID: 32726803 Free PMC article.
Mechanism and inhibition of the papain-like protease, PLpro, of SARS-CoV-2.
Klemm T, Ebert G, Calleja DJ, Allison CC, Richardson LW, Bernardini JP, Lu BG, Kuchel NW, Grohmann C, Shibata Y, Gan ZY, Cooney JP, Doerflinger M, Au AE, Blackmore TR, van der Heden van Noort GJ, Geurink PP, Ovaa H, Newman J, Riboldi-Tunnicliffe A, Czabotar PE, Mitchell JP, Feltham R, Lechtenberg BC, Lowes KN, Dewson G, Pellegrini M, Lessene G, Komander D. Klemm T, et al. Among authors: van der heden van noort gj. EMBO J. 2020 Sep 15;39(18):e106275. doi: 10.15252/embj.2020106275. Epub 2020 Aug 26. EMBO J. 2020. PMID: 32845033 Free PMC article.
An RNA virus hijacks an incognito function of a DNA repair enzyme.
Virgen-Slane R, Rozovics JM, Fitzgerald KD, Ngo T, Chou W, van der Heden van Noort GJ, Filippov DV, Gershon PD, Semler BL. Virgen-Slane R, et al. Among authors: van der heden van noort gj. Proc Natl Acad Sci U S A. 2012 Sep 4;109(36):14634-9. doi: 10.1073/pnas.1208096109. Epub 2012 Aug 20. Proc Natl Acad Sci U S A. 2012. PMID: 22908287 Free PMC article.
Modification of picornavirus genomic RNA using 'click' chemistry shows that unlinking of the VPg peptide is dispensable for translation and replication of the incoming viral RNA.
Langereis MA, Feng Q, Nelissen FH, Virgen-Slane R, van der Heden van Noort GJ, Maciejewski S, Filippov DV, Semler BL, van Delft FL, van Kuppeveld FJ. Langereis MA, et al. Among authors: van der heden van noort gj, van delft fl, van kuppeveld fj. Nucleic Acids Res. 2014 Feb;42(4):2473-82. doi: 10.1093/nar/gkt1162. Epub 2013 Nov 15. Nucleic Acids Res. 2014. PMID: 24243841 Free PMC article.
State of the art in (semi-)synthesis of Ubiquitin- and Ubiquitin-like tools.
Huppelschoten Y, van der Heden van Noort GJ. Huppelschoten Y, et al. Among authors: van der heden van noort gj. Semin Cell Dev Biol. 2022 Dec;132:74-85. doi: 10.1016/j.semcdb.2021.11.025. Epub 2021 Dec 24. Semin Cell Dev Biol. 2022. PMID: 34961664 Free article. Review.
54 results