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Page 1
CERT1 mutations perturb human development by disrupting sphingolipid homeostasis.
Gehin C, Lone MA, Lee W, Capolupo L, Ho S, Adeyemi AM, Gerkes EH, Stegmann AP, López-Martín E, Bermejo-Sánchez E, Martínez-Delgado B, Zweier C, Kraus C, Popp B, Strehlow V, Gräfe D, Knerr I, Jones ER, Zamuner S, Abriata LA, Kunnathully V, Moeller BE, Vocat A, Rommelaere S, Bocquete JP, Ruchti E, Limoni G, Van Campenhoudt M, Bourgeat S, Henklein P, Gilissen C, van Bon BW, Pfundt R, Willemsen MH, Schieving JH, Leonardi E, Soli F, Murgia A, Guo H, Zhang Q, Xia K, Fagerberg CR, Beier CP, Larsen MJ, Valenzuela I, Fernández-Álvarez P, Xiong S, Śmigiel R, López-González V, Armengol L, Morleo M, Selicorni A, Torella A, Blyth M, Cooper NS, Wilson V, Oegema R, Herenger Y, Garde A, Bruel AL, Tran Mau-Them F, Maddocks AB, Bain JM, Bhat MA, Costain G, Kannu P, Marwaha A, Champaigne NL, Friez MJ, Richardson EB, Gowda VK, Srinivasan VM, Gupta Y, Lim TY, Sanna-Cherchi S, Lemaitre B, Yamaji T, Hanada K, Burke JE, Jakšić AM, McCabe BD, De Los Rios P, Hornemann T, D'Angelo G, Gennarino VA. Gehin C, et al. Among authors: moeller be. J Clin Invest. 2023 May 15;133(10):e165019. doi: 10.1172/JCI165019. J Clin Invest. 2023. PMID: 36976648 Free PMC article.
Crystal structure of an archaeal CorB magnesium transporter.
Chen YS, Kozlov G, Moeller BE, Rohaim A, Fakih R, Roux B, Burke JE, Gehring K. Chen YS, et al. Among authors: moeller be. Nat Commun. 2021 Jun 29;12(1):4028. doi: 10.1038/s41467-021-24282-7. Nat Commun. 2021. PMID: 34188059 Free PMC article.
Impaired host resistance to Salmonella during helminth co-infection is restored by anthelmintic treatment prior to bacterial challenge.
Brosschot TP, Lawrence KM, Moeller BE, Kennedy MHE, FitzPatrick RD, Gauthier CM, Shin D, Gatti DM, Conway KME, Reynolds LA. Brosschot TP, et al. Among authors: moeller be. PLoS Negl Trop Dis. 2021 Jan 20;15(1):e0009052. doi: 10.1371/journal.pntd.0009052. eCollection 2021 Jan. PLoS Negl Trop Dis. 2021. PMID: 33471793 Free PMC article.
Allosteric activation or inhibition of PI3Kγ mediated through conformational changes in the p110γ helical domain.
Harris NJ, Jenkins ML, Nam SE, Rathinaswamy MK, Parson MA, Ranga-Prasad H, Dalwadi U, Moeller BE, Sheekey E, Hansen SD, Yip CK, Burke JE. Harris NJ, et al. Among authors: moeller be. bioRxiv [Preprint]. 2023 May 23:2023.04.12.536585. doi: 10.1101/2023.04.12.536585. bioRxiv. 2023. Update in: Elife. 2023 Jul 07;12:RP88058. doi: 10.7554/eLife.88058 PMID: 37090531 Free PMC article. Updated. Preprint.
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