Goradia A - Search Results

1

The phenotype of the most common human ADAR1p150 Zα mutation P193A in mice is partially penetrant.

Liang Z, Chalk AM, Taylor S, Goradia A, Heraud-Farlow JE, Walkley CR. Liang Z, et al. Among authors: goradia a. EMBO Rep. 2023 May 4;24(5):e55835. doi: 10.15252/embr.202255835. Epub 2023 Mar 28. EMBO Rep. 2023. PMID: 36975179 Free PMC article.

2

Modeling distinct osteosarcoma subtypes in vivo using Cre:lox and lineage-restricted transgenic shRNA.

Mutsaers AJ, Ng AJ, Baker EK, Russell MR, Chalk AM, Wall M, Liddicoat BJ, Ho PW, Slavin JL, Goradia A, Martin TJ, Purton LE, Dickins RA, Walkley CR. Mutsaers AJ, et al. Among authors: goradia a. Bone. 2013 Jul;55(1):166-78. doi: 10.1016/j.bone.2013.02.016. Epub 2013 Feb 26. Bone. 2013. PMID: 23486187

3

Knockdown of PTHR1 in osteosarcoma cells decreases invasion and growth and increases tumor differentiation in vivo.

Ho PW, Goradia A, Russell MR, Chalk AM, Milley KM, Baker EK, Danks JA, Slavin JL, Walia M, Crimeen-Irwin B, Dickins RA, Martin TJ, Walkley CR. Ho PW, et al. Among authors: goradia a. Oncogene. 2015 May 28;34(22):2922-33. doi: 10.1038/onc.2014.217. Epub 2014 Jul 21. Oncogene. 2015. PMID: 25043296

4

Over-expression of ADAR1 in mice does not initiate or accelerate cancer formation in vivo.

Mendez Ruiz S, Chalk AM, Goradia A, Heraud-Farlow J, Walkley CR. Mendez Ruiz S, et al. Among authors: goradia a. NAR Cancer. 2023 Jun 1;5(2):zcad023. doi: 10.1093/narcan/zcad023. eCollection 2023 Jun. NAR Cancer. 2023. PMID: 37275274 Free PMC article.

5

Generation of a new Adar1p150 ^-/- mouse demonstrates isoform-specific roles in embryonic development and adult homeostasis.

Liang Z, Goradia A, Walkley CR, Heraud-Farlow JE. Liang Z, et al. Among authors: goradia a. RNA. 2023 Sep;29(9):1325-1338. doi: 10.1261/rna.079509.122. Epub 2023 Jun 8. RNA. 2023. PMID: 37290963 Free PMC article.

6

A kinase-dead allele of Lyn attenuates autoimmune disease normally associated with Lyn deficiency.

Verhagen AM, Wallace ME, Goradia A, Jones SA, Croom HA, Metcalf D, Collinge JE, Maxwell MJ, Hibbs ML, Alexander WS, Hilton DJ, Kile BT, Starr R. Verhagen AM, et al. Among authors: goradia a. J Immunol. 2009 Feb 15;182(4):2020-9. doi: 10.4049/jimmunol.0803127. J Immunol. 2009. PMID: 19201855

7

SOCS-1 binding to tyrosine 441 of IFN-gamma receptor subunit 1 contributes to the attenuation of IFN-gamma signaling in vivo.

Starr R, Fuchsberger M, Lau LS, Uldrich AP, Goradia A, Willson TA, Verhagen AM, Alexander WS, Smyth MJ. Starr R, et al. Among authors: goradia a. J Immunol. 2009 Oct 1;183(7):4537-44. doi: 10.4049/jimmunol.0901010. Epub 2009 Sep 4. J Immunol. 2009. PMID: 19734231

8

GGNBP2 regulates MDA5 sensing triggered by self double-stranded RNA following loss of ADAR1 editing.

Heraud-Farlow JE, Taylor SR, Chalk AM, Escudero A, Hu SB, Goradia A, Sun T, Li Q, Nikolic I, Li JB, Fidalgo M, Guallar D, Simpson KJ, Walkley CR. Heraud-Farlow JE, et al. Among authors: goradia a. Sci Immunol. 2024 Nov 22;9(101):eadk0412. doi: 10.1126/sciimmunol.adk0412. Epub 2024 Nov 22. Sci Immunol. 2024. PMID: 39576872

9

ADAR1p150 prevents MDA5 and PKR activation via distinct mechanisms to avert fatal autoinflammation.

Hu SB, Heraud-Farlow J, Sun T, Liang Z, Goradia A, Taylor S, Walkley CR, Li JB. Hu SB, et al. Among authors: goradia a. Mol Cell. 2023 Nov 2;83(21):3869-3884.e7. doi: 10.1016/j.molcel.2023.09.018. Epub 2023 Oct 4. Mol Cell. 2023. PMID: 37797622 Free article.

10

ADAR1p150 Prevents MDA5 and PKR Activation via Distinct Mechanisms to Avert Fatal Autoinflammation.

Hu SB, Heraud-Farlow J, Sun T, Liang Z, Goradia A, Taylor S, Walkley CR, Li JB. Hu SB, et al. Among authors: goradia a. bioRxiv [Preprint]. 2023 Jan 25:2023.01.25.525475. doi: 10.1101/2023.01.25.525475. bioRxiv. 2023. Update in: Mol Cell. 2023 Nov 2;83(21):3869-3884.e7. doi: 10.1016/j.molcel.2023.09.018 PMID: 36747811 Free PMC article. Updated. Preprint.

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