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Unraveling an Alternative Mechanism in Polymer Self-Assemblies: An Order-Order Transition with Unusual Molecular Interactions between Hydrophilic and Hydrophobic Polymer Blocks.
Hahn L, Zorn T, Kehrein J, Kielholz T, Ziegler AL, Forster S, Sochor B, Lisitsyna ES, Durandin NA, Laaksonen T, Aseyev V, Sotriffer C, Saalwächter K, Windbergs M, Pöppler AC, Luxenhofer R. Hahn L, et al. Among authors: kehrein j. ACS Nano. 2023 Apr 11;17(7):6932-6942. doi: 10.1021/acsnano.3c00722. Epub 2023 Mar 27. ACS Nano. 2023. PMID: 36972400 Free PMC article.
Controlling Supramolecular Structures of Drugs by Light.
Wiest J, Kehrein J, Saedtler M, Schilling K, Cataldi E, Sotriffer CA, Holzgrabe U, Rasmussen T, Böttcher B, Cronin-Golomb M, Lehmann M, Jung N, Windbergs M, Meinel L. Wiest J, et al. Among authors: kehrein j. Mol Pharm. 2020 Dec 7;17(12):4704-4708. doi: 10.1021/acs.molpharmaceut.0c00720. Epub 2020 Oct 29. Mol Pharm. 2020. PMID: 33118829
A Long Residence Time Enoyl-Reductase Inhibitor Explores an Extended Binding Region with Isoenzyme-Dependent Tautomer Adaptation and Differential Substrate-Binding Loop Closure.
Eltschkner S, Kehrein J, Le TA, Davoodi S, Merget B, Basak S, Weinrich JD, Schiebel J, Tonge PJ, Engels B, Sotriffer C, Kisker C. Eltschkner S, et al. Among authors: kehrein j. ACS Infect Dis. 2021 Apr 9;7(4):746-758. doi: 10.1021/acsinfecdis.0c00437. Epub 2021 Mar 12. ACS Infect Dis. 2021. PMID: 33710875 Free PMC article.
Predicting Bile and Lipid Interaction for Drug Substances.
Schlauersbach J, Kehrein J, Hanio S, Galli B, Harlacher C, Heidenreich C, Lenz B, Sotriffer C, Meinel L. Schlauersbach J, et al. Among authors: kehrein j. Mol Pharm. 2022 Aug 1;19(8):2868-2876. doi: 10.1021/acs.molpharmaceut.2c00227. Epub 2022 Jul 1. Mol Pharm. 2022. PMID: 35776440
Deciphering Polymer Interactions in Bioconjugates with Different Architectures by Structural Analysis via Time-Resolved Limited Proteolysis Mass Spectrometry.
Hamm P, Driessen MD, Hauptstein N, Kehrein J, Worschech R, Pouyan P, Haag R, Schubert US, Müller TD, Meinel L, Lühmann T. Hamm P, et al. Among authors: kehrein j. Angew Chem Int Ed Engl. 2025 Jan 9:e202415354. doi: 10.1002/anie.202415354. Online ahead of print. Angew Chem Int Ed Engl. 2025. PMID: 39780761
12 results