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In vivo evidence that RBM5 is a tumour suppressor in the lung.
Jamsai D, Watkins DN, O'Connor AE, Merriner DJ, Gursoy S, Bird AD, Kumar B, Miller A, Cole TJ, Jenkins BJ, O'Bryan MK. Jamsai D, et al. Among authors: kumar b. Sci Rep. 2017 Nov 24;7(1):16323. doi: 10.1038/s41598-017-15874-9. Sci Rep. 2017. PMID: 29176597 Free PMC article.
STAT3-mediated upregulation of the AIM2 DNA sensor links innate immunity with cell migration to promote epithelial tumourigenesis.
Dawson RE, Deswaerte V, West AC, Tang K, West AJ, Balic JJ, Gearing LJ, Saad MI, Yu L, Wu Y, Bhathal PS, Kumar B, Chakrabarti JT, Zavros Y, Oshima H, Klinman DM, Oshima M, Tan P, Jenkins BJ. Dawson RE, et al. Among authors: kumar b. Gut. 2022 Aug;71(8):1515-1531. doi: 10.1136/gutjnl-2020-323916. Epub 2021 Sep 6. Gut. 2022. PMID: 34489308
Oncogenic dependency on STAT3 serine phosphorylation in KRAS mutant lung cancer.
Alhayyani S, McLeod L, West AC, Balic JJ, Hodges C, Yu L, Smith JA, Prodanovic Z, Bozinovski S, Kumar B, Ruwanpura SM, Saad MI, Jenkins BJ. Alhayyani S, et al. Among authors: kumar b. Oncogene. 2022 Feb;41(6):809-823. doi: 10.1038/s41388-021-02134-4. Epub 2021 Dec 3. Oncogene. 2022. PMID: 34857889
Blockade of the protease ADAM17 ameliorates experimental pancreatitis.
Saad MI, Weng T, Lundy J, Gearing LJ, West AC, Harpur CM, Alanazi M, Hodges C, Croagh D, Kumar B, Sagi I, Rose-John S, Jenkins BJ. Saad MI, et al. Among authors: kumar b. Proc Natl Acad Sci U S A. 2022 Oct 18;119(42):e2213744119. doi: 10.1073/pnas.2213744119. Epub 2022 Oct 10. Proc Natl Acad Sci U S A. 2022. PMID: 36215509 Free PMC article.
Mitochondrial DNA plasticity is an essential inducer of tumorigenesis.
Lee WT, Cain JE, Cuddihy A, Johnson J, Dickinson A, Yeung KY, Kumar B, Johns TG, Watkins DN, Spencer A, St John JC. Lee WT, et al. Among authors: kumar b. Cell Death Discov. 2016 Apr 4;2:16016. doi: 10.1038/cddiscovery.2016.16. eCollection 2016. Cell Death Discov. 2016. PMID: 27551510 Free PMC article.
4,042 results