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Page 1
Aiolos represses CD4+ T cell cytotoxic programming via reciprocal regulation of TFH transcription factors and IL-2 sensitivity.
Read KA, Jones DM, Pokhrel S, Hales EDS, Varkey A, Tuazon JA, Eisele CD, Abdouni O, Saadey A, Leonard MR, Warren RT, Powell MD, Boss JM, Hemann EA, Yount JS, Xin G, Ghoneim HE, Lio CJ, Freud AG, Collins PL, Oestreich KJ. Read KA, et al. Among authors: ghoneim he. Nat Commun. 2023 Mar 24;14(1):1652. doi: 10.1038/s41467-023-37420-0. Nat Commun. 2023. PMID: 36964178 Free PMC article.
Gene Regulatory Circuits in Innate and Adaptive Immune Cells.
Saini A, Ghoneim HE, Lio CJ, Collins PL, Oltz EM. Saini A, et al. Among authors: ghoneim he. Annu Rev Immunol. 2022 Apr 26;40:387-411. doi: 10.1146/annurev-immunol-101320-025949. Epub 2022 Feb 4. Annu Rev Immunol. 2022. PMID: 35119910 Free PMC article. Review.
Epigenetic remodeling by vitamin C potentiates plasma cell differentiation.
Chen HY, Almonte-Loya A, Lay FY, Hsu M, Johnson E, González-Avalos E, Yin J, Bruno RS, Ma Q, Ghoneim HE, Wozniak DJ, Harrison FE, Lio CJ. Chen HY, et al. Among authors: ghoneim he. Elife. 2022 Sep 7;11:e73754. doi: 10.7554/eLife.73754. Elife. 2022. PMID: 36069787 Free PMC article.
TOX reinforces the phenotype and longevity of exhausted T cells in chronic viral infection.
Alfei F, Kanev K, Hofmann M, Wu M, Ghoneim HE, Roelli P, Utzschneider DT, von Hoesslin M, Cullen JG, Fan Y, Eisenberg V, Wohlleber D, Steiger K, Merkler D, Delorenzi M, Knolle PA, Cohen CJ, Thimme R, Youngblood B, Zehn D. Alfei F, et al. Among authors: ghoneim he. Nature. 2019 Jul;571(7764):265-269. doi: 10.1038/s41586-019-1326-9. Epub 2019 Jun 17. Nature. 2019. PMID: 31207605
Functional T cells are capable of supernumerary cell division and longevity.
Soerens AG, Künzli M, Quarnstrom CF, Scott MC, Swanson L, Locquiao JJ, Ghoneim HE, Zehn D, Youngblood B, Vezys V, Masopust D. Soerens AG, et al. Among authors: ghoneim he. Nature. 2023 Feb;614(7949):762-766. doi: 10.1038/s41586-022-05626-9. Epub 2023 Jan 18. Nature. 2023. PMID: 36653453 Free PMC article.
Effector CD8 T cells dedifferentiate into long-lived memory cells.
Youngblood B, Hale JS, Kissick HT, Ahn E, Xu X, Wieland A, Araki K, West EE, Ghoneim HE, Fan Y, Dogra P, Davis CW, Konieczny BT, Antia R, Cheng X, Ahmed R. Youngblood B, et al. Among authors: ghoneim he. Nature. 2017 Dec 21;552(7685):404-409. doi: 10.1038/nature25144. Epub 2017 Dec 13. Nature. 2017. PMID: 29236683 Free PMC article.
T cell exhaustion-a memory locked behind scars.
Yousif A, Ghoneim HE. Yousif A, et al. Among authors: ghoneim he. Nat Immunol. 2021 Aug;22(8):938-940. doi: 10.1038/s41590-021-00977-3. Nat Immunol. 2021. PMID: 34312546 No abstract available.
Beta cell-specific CD8+ T cells maintain stem cell memory-associated epigenetic programs during type 1 diabetes.
Abdelsamed HA, Zebley CC, Nguyen H, Rutishauser RL, Fan Y, Ghoneim HE, Crawford JC, Alfei F, Alli S, Ribeiro SP, Castellaw AH, McGargill MA, Jin H, Boi SK, Speake C, Serti E, Turka LA, Busch ME, Stone M, Deeks SG, Sekaly RP, Zehn D, James EA, Nepom GT, Youngblood B. Abdelsamed HA, et al. Among authors: ghoneim he. Nat Immunol. 2020 May;21(5):578-587. doi: 10.1038/s41590-020-0633-5. Epub 2020 Mar 30. Nat Immunol. 2020. PMID: 32231298 Free PMC article.
Influenza A virus directly modulates mouse eosinophil responses.
LeMessurier KS, Rooney R, Ghoneim HE, Liu B, Li K, Smallwood HS, Samarasinghe AE. LeMessurier KS, et al. Among authors: ghoneim he. J Leukoc Biol. 2020 Jul;108(1):151-168. doi: 10.1002/JLB.4MA0320-343R. Epub 2020 May 9. J Leukoc Biol. 2020. PMID: 32386457 Free PMC article.
28 results