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Noncoding regions are the main source of targetable tumor-specific antigens.
Laumont CM, Vincent K, Hesnard L, Audemard É, Bonneil É, Laverdure JP, Gendron P, Courcelles M, Hardy MP, Côté C, Durette C, St-Pierre C, Benhammadi M, Lanoix J, Vobecky S, Haddad E, Lemieux S, Thibault P, Perreault C. Laumont CM, et al. Among authors: lanoix j. Sci Transl Med. 2018 Dec 5;10(470):eaau5516. doi: 10.1126/scitranslmed.aau5516. Sci Transl Med. 2018. PMID: 30518613
Proteogenomics Uncovers a Vast Repertoire of Shared Tumor-Specific Antigens in Ovarian Cancer.
Zhao Q, Laverdure JP, Lanoix J, Durette C, Côté C, Bonneil É, Laumont CM, Gendron P, Vincent K, Courcelles M, Lemieux S, Millar DG, Ohashi PS, Thibault P, Perreault C. Zhao Q, et al. Among authors: lanoix j. Cancer Immunol Res. 2020 Apr;8(4):544-555. doi: 10.1158/2326-6066.CIR-19-0541. Epub 2020 Feb 11. Cancer Immunol Res. 2020. PMID: 32047025
Most non-canonical proteins uniquely populate the proteome or immunopeptidome.
Ruiz Cuevas MV, Hardy MP, Hollý J, Bonneil É, Durette C, Courcelles M, Lanoix J, Côté C, Staudt LM, Lemieux S, Thibault P, Perreault C, Yewdell JW. Ruiz Cuevas MV, et al. Among authors: lanoix j. Cell Rep. 2021 Mar 9;34(10):108815. doi: 10.1016/j.celrep.2021.108815. Cell Rep. 2021. PMID: 33691108 Free PMC article.
123 results