Kindon ND - Search Results

1

Small-Molecule Fluorescent Ligands for the CXCR4 Chemokine Receptor.

Dekkers S, Caspar B, Goulding J, Kindon ND, Kilpatrick LE, Stoddart LA, Briddon SJ, Kellam B, Hill SJ, Stocks MJ. Dekkers S, et al. Among authors: kindon nd. J Med Chem. 2023 Apr 13;66(7):5208-5222. doi: 10.1021/acs.jmedchem.3c00151. Epub 2023 Mar 21. J Med Chem. 2023. PMID: 36944083 Free PMC article.

2

Drug-like Antagonists of P2Y Receptors-From Lead Identification to Drug Development.

Conroy S, Kindon N, Kellam B, Stocks MJ. Conroy S, et al. J Med Chem. 2016 Nov 23;59(22):9981-10005. doi: 10.1021/acs.jmedchem.5b01972. Epub 2016 Aug 1. J Med Chem. 2016. PMID: 27413802 Review.

3

Design and Elaboration of a Tractable Tricyclic Scaffold To Synthesize Druglike Inhibitors of Dipeptidyl Peptidase-4 (DPP-4), Antagonists of the C-C Chemokine Receptor Type 5 (CCR5), and Highly Potent and Selective Phosphoinositol-3 Kinase δ (PI3Kδ) Inhibitors.

Schwehm C, Kellam B, Garces AE, Hill SJ, Kindon ND, Bradshaw TD, Li J, Macdonald SJ, Rowedder JE, Stoddart LA, Stocks MJ. Schwehm C, et al. Among authors: kindon nd. J Med Chem. 2017 Feb 23;60(4):1534-1554. doi: 10.1021/acs.jmedchem.6b01801. Epub 2017 Feb 10. J Med Chem. 2017. PMID: 28128944 Free article.

4

Synthesis and Evaluation of the First Fluorescent Antagonists of the Human P2Y₂ Receptor Based on AR-C118925.

Conroy S, Kindon ND, Glenn J, Stoddart LA, Lewis RJ, Hill SJ, Kellam B, Stocks MJ. Conroy S, et al. Among authors: kindon nd. J Med Chem. 2018 Apr 12;61(7):3089-3113. doi: 10.1021/acs.jmedchem.8b00139. Epub 2018 Mar 28. J Med Chem. 2018. PMID: 29558126 Free PMC article.

5

Subtype-Selective Fluorescent Ligands as Pharmacological Research Tools for the Human Adenosine A_2A Receptor.

Comeo E, Kindon ND, Soave M, Stoddart LA, Kilpatrick LE, Scammells PJ, Hill SJ, Kellam B. Comeo E, et al. Among authors: kindon nd. J Med Chem. 2020 Mar 12;63(5):2656-2672. doi: 10.1021/acs.jmedchem.9b01856. Epub 2020 Jan 9. J Med Chem. 2020. PMID: 31887252 Free article.

6

Development and Application of Subtype-Selective Fluorescent Antagonists for the Study of the Human Adenosine A₁ Receptor in Living Cells.

Comeo E, Trinh P, Nguyen AT, Nowell CJ, Kindon ND, Soave M, Stoddart LA, White JM, Hill SJ, Kellam B, Halls ML, May LT, Scammells PJ. Comeo E, et al. Among authors: kindon nd. J Med Chem. 2021 May 27;64(10):6670-6695. doi: 10.1021/acs.jmedchem.0c02067. Epub 2021 Mar 16. J Med Chem. 2021. PMID: 33724031 Free article.

7

Correction to Synthesis and Evaluation of the First Fluorescent Antagonists of the Human P2Y₂ Receptor Based on AR-C118925.

Conroy S, Kindon ND, Glenn J, Stoddart LA, Lewis RJ, Hill SJ, Kellam B, Stocks MJ. Conroy S, et al. Among authors: kindon nd. J Med Chem. 2018 May 10;61(9):4272. doi: 10.1021/acs.jmedchem.8b00606. Epub 2018 Apr 24. J Med Chem. 2018. PMID: 29688707 Free PMC article. No abstract available.

8

Ligand-directed covalent labelling of a GPCR with a fluorescent tag in live cells.

Stoddart LA, Kindon ND, Otun O, Harwood CR, Patera F, Veprintsev DB, Woolard J, Briddon SJ, Franks HA, Hill SJ, Kellam B. Stoddart LA, et al. Among authors: kindon nd. Commun Biol. 2020 Nov 27;3(1):722. doi: 10.1038/s42003-020-01451-w. Commun Biol. 2020. PMID: 33247190 Free PMC article.

9

From UTP to AR-C118925, the discovery of a potent non nucleotide antagonist of the P2Y₂ receptor.

Kindon N, Davis A, Dougall I, Dixon J, Johnson T, Walters I, Thom S, McKechnie K, Meghani P, Stocks MJ. Kindon N, et al. Bioorg Med Chem Lett. 2017 Nov 1;27(21):4849-4853. doi: 10.1016/j.bmcl.2017.09.043. Epub 2017 Sep 21. Bioorg Med Chem Lett. 2017. PMID: 28958619

10

The discovery of new spirocyclic muscarinic M3 antagonists.

Stocks MJ, Alcaraz L, Bailey A, Bowers K, Donald D, Edwards H, Hunt F, Kindon N, Pairaudeau G, Theaker J, Warner DJ. Stocks MJ, et al. Bioorg Med Chem Lett. 2010 Dec 15;20(24):7458-61. doi: 10.1016/j.bmcl.2010.10.016. Epub 2010 Oct 28. Bioorg Med Chem Lett. 2010. PMID: 21036043

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