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Engineering olivocochlear inhibition to reduce acoustic trauma.
Zhang Y, Hiel H, Vincent PFY, Wood MB, Elgoyhen AB, Chien W, Lauer A, Fuchs PA. Zhang Y, et al. Among authors: chien w. Mol Ther Methods Clin Dev. 2023 Feb 26;29:17-31. doi: 10.1016/j.omtm.2023.02.011. eCollection 2023 Jun 8. Mol Ther Methods Clin Dev. 2023. PMID: 36941920 Free PMC article.
Dual-AAV vector-mediated expression of MYO7A improves vestibular function in a mouse model of Usher syndrome 1B.
Lau SC, Grati M, Isgrig K, Sinan M, Calabro KR, Zhu J, Ishibashi Y, Ozgur Z, Wafa T, Belyantseva IA, Fitzgerald T, Friedman TB, Boye SL, Boye SE, Chien WW. Lau SC, et al. Among authors: chien ww. Mol Ther Methods Clin Dev. 2023 Aug 21;30:534-545. doi: 10.1016/j.omtm.2023.08.012. eCollection 2023 Sep 14. Mol Ther Methods Clin Dev. 2023. PMID: 37693946 Free PMC article.
Gene Therapy Restores Balance and Auditory Functions in a Mouse Model of Usher Syndrome.
Isgrig K, Shteamer JW, Belyantseva IA, Drummond MC, Fitzgerald TS, Vijayakumar S, Jones SM, Griffith AJ, Friedman TB, Cunningham LL, Chien WW. Isgrig K, et al. Among authors: chien ww. Mol Ther. 2017 Mar 1;25(3):780-791. doi: 10.1016/j.ymthe.2017.01.007. Epub 2017 Feb 21. Mol Ther. 2017. PMID: 28254438 Free PMC article.
AAV2.7m8 is a powerful viral vector for inner ear gene therapy.
Isgrig K, McDougald DS, Zhu J, Wang HJ, Bennett J, Chien WW. Isgrig K, et al. Among authors: chien ww. Nat Commun. 2019 Jan 25;10(1):427. doi: 10.1038/s41467-018-08243-1. Nat Commun. 2019. PMID: 30683875 Free PMC article.
1,071 results