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Pathogenic PTPN11 variants involving the poly-glutamine Gln255 -Gln256 -Gln257 stretch highlight the relevance of helix B in SHP2's functional regulation.
Martinelli S, Pannone L, Lissewski C, Brinkmann J, Flex E, Schanze D, Calligari P, Anselmi M, Pantaleoni F, Canale VC, Radio FC, Ioannides A, Rahner N, Schanze I, Josifova D, Bocchinfuso G, Ryten M, Stella L, Tartaglia M, Zenker M. Martinelli S, et al. Among authors: ioannides a. Hum Mutat. 2020 Jun;41(6):1171-1182. doi: 10.1002/humu.24007. Epub 2020 Mar 11. Hum Mutat. 2020. PMID: 32112654
Association of inflammatory cytokines with lung function, chronic lung diseases, and COVID-19.
Rontogianni MO, Gill D, Bouras E, Asimakopoulos AG, Tzoulaki I, Karhunen V, Lehtimäki T, Raitakari O, Wielscher M, Salomaa V, Jalkanen S, Salmi M, Timonen M, Yarmolinsky J, Chen J, Tobin MD, Izquierdo AG, Herzig KH, Ioannides AE, Jarvelin MR, Dehghan A, Tsilidis KK. Rontogianni MO, et al. Among authors: ioannides ae. iScience. 2024 Aug 9;27(10):110704. doi: 10.1016/j.isci.2024.110704. eCollection 2024 Oct 18. iScience. 2024. PMID: 39319267 Free PMC article.
Transcatheter Valve Repair in Heart Failure with Moderate to Severe Mitral Regurgitation.
Anker SD, Friede T, von Bardeleben RS, Butler J, Khan MS, Diek M, Heinrich J, Geyer M, Placzek M, Ferrari R, Abraham WT, Alfieri O, Auricchio A, Bayes-Genis A, Cleland JGF, Filippatos G, Gustafsson F, Haverkamp W, Kelm M, Kuck KH, Landmesser U, Maggioni AP, Metra M, Ninios V, Petrie MC, Rassaf T, Ruschitzka F, Schäfer U, Schulze PC, Spargias K, Vahanian A, Zamorano JL, Zeiher A, Karakas M, Koehler F, Lainscak M, Öner A, Mezilis N, Theofilogiannakos EK, Ninios I, Chrissoheris M, Kourkoveli P, Papadopoulos K, Smolka G, Wojakowski W, Reczuch K, Pinto FJ, Wiewiórka Ł, Kalarus Z, Adamo M, Santiago-Vacas E, Ruf TF, Gross M, Tongers J, Hasenfuss G, Schillinger W, Ponikowski P; RESHAPE-HF2 Investigators. Anker SD, et al. N Engl J Med. 2024 Nov 14;391(19):1799-1809. doi: 10.1056/NEJMoa2314328. Epub 2024 Aug 31. N Engl J Med. 2024. PMID: 39216092 Clinical Trial.
137 results