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Pharmacological Inhibition of STAT3 by Stattic Ameliorates Clinical Symptoms and Reduces Autoinflammation in Myeloid, Lymphoid, and Neuronal Tissue Compartments in Relapsing-Remitting Model of Experimental Autoimmune Encephalomyelitis in SJL/J Mice.
Alhazzani K, Ahmad SF, Al-Harbi NO, Attia SM, Bakheet SA, Sarawi W, Alqarni SA, Algahtani M, Nadeem A. Alhazzani K, et al. Among authors: alqarni sa. Pharmaceutics. 2021 Jun 22;13(7):925. doi: 10.3390/pharmaceutics13070925. Pharmaceutics. 2021. PMID: 34206429 Free PMC article.
Role of ITK signaling in acute kidney injury in mice: Amelioration of acute kidney injury associated clinical parameters and attenuation of inflammatory transcription factor signaling in CD4+ T cells by ITK inhibition.
Nadeem A, Ahmad SF, Al-Harbi NO, Ibrahim KE, Sarawi W, Attia SM, Alasmari AF, Alqarni SA, Alfradan AS, Bakheet SA, Al-Harbi MM. Nadeem A, et al. Among authors: alqarni sa. Int Immunopharmacol. 2021 Oct;99:108028. doi: 10.1016/j.intimp.2021.108028. Epub 2021 Aug 5. Int Immunopharmacol. 2021. PMID: 34365077
Acetyl-11-keto-β-boswellic acid improves clinical symptoms through modulation of Nrf2 and NF-κB pathways in SJL/J mouse model of experimental autoimmune encephalomyelitis.
Nadeem A, Ahmad SF, Al-Harbi NO, Sarawi W, Attia SM, Alanazi WA, Ibrahim KE, Alsanea S, Alqarni SA, Alfardan AS, Bakheet SA. Nadeem A, et al. Among authors: alqarni sa. Int Immunopharmacol. 2022 Jun;107:108703. doi: 10.1016/j.intimp.2022.108703. Epub 2022 Mar 17. Int Immunopharmacol. 2022. PMID: 35306283
Lck signaling inhibition causes improvement in clinical features of psoriatic inflammation through reduction in inflammatory cytokines in CD4+ T cells in imiquimod mouse model.
Al-Harbi NO, Ahmad SF, Almutairi M, Alanazi AZ, Ibrahim KE, Alqarni SA, Alqahtani F, Alhazzani K, Alharbi M, Alasmari F, Nadeem A. Al-Harbi NO, et al. Among authors: alqarni sa. Cell Immunol. 2022 Jun;376:104531. doi: 10.1016/j.cellimm.2022.104531. Epub 2022 May 13. Cell Immunol. 2022. PMID: 35576719
Bruton's tyrosine kinase inhibition suppresses neutrophilic inflammation and restores histone deacetylase 2 expression in myeloid and structural cells in a mixed granulocytic mouse model of asthma.
Nadeem A, Alshehri S, Al-Harbi NO, Ahmad SF, Albekairi NA, Alqarni SA, Ibrahim KE, Alfardan AS, Alshamrani AA, Bin Salman SB, Attia SM. Nadeem A, et al. Among authors: alqarni sa. Int Immunopharmacol. 2023 Apr;117:109920. doi: 10.1016/j.intimp.2023.109920. Epub 2023 Feb 23. Int Immunopharmacol. 2023. PMID: 36827920
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