Rovira C - Search Results

1

Glycosidase mechanisms: Sugar conformations and reactivity in endo- and exo-acting enzymes.

Morais MAB, Nin-Hill A, Rovira C. Morais MAB, et al. Among authors: rovira c. Curr Opin Chem Biol. 2023 Jun;74:102282. doi: 10.1016/j.cbpa.2023.102282. Epub 2023 Mar 15. Curr Opin Chem Biol. 2023. PMID: 36931022 Free article. Review.

2

4-O-Substituted Glucuronic Cyclophellitols are Selective Mechanism-Based Heparanase Inhibitors.

Borlandelli V, Armstrong Z, Nin-Hill A, Codée JDC, Raich L, Artola M, Rovira C, Davies GJ, Overkleeft HS. Borlandelli V, et al. Among authors: rovira c. ChemMedChem. 2023 Feb 14;18(4):e202200580. doi: 10.1002/cmdc.202200580. Epub 2023 Jan 24. ChemMedChem. 2023. PMID: 36533564 Free PMC article.

3

Control of Substrate Conformation by Hydrogen Bonding in a Retaining β-Endoglycosidase.

Nin-Hill A, Ardevol A, Biarnés X, Planas A, Rovira C. Nin-Hill A, et al. Among authors: rovira c. Chemistry. 2023 Dec 14;29(70):e202302555. doi: 10.1002/chem.202302555. Epub 2023 Oct 25. Chemistry. 2023. PMID: 37804517

4

Conformational and Electronic Variations in 1,2- and 1,5a-Cyclophellitols and their Impact on Retaining α-Glucosidase Inhibition.

Ofman TP, Heming JJA, Nin-Hill A, Küllmer F, Moran E, Bennett M, Steneker R, Klein AM, Ruijgrok G, Kok K, Armstrong ZWB, Aerts JMFG, van der Marel GA, Rovira C, Davies GJ, Artola M, Codée JDC, Overkleeft HS. Ofman TP, et al. Among authors: rovira c. Chemistry. 2024 Jun 3;30(31):e202400723. doi: 10.1002/chem.202400723. Epub 2024 Apr 24. Chemistry. 2024. PMID: 38623783

5

Unlocking the specificity of antimicrobial peptide interactions for membrane-targeted therapies.

Conde-Torres D, Calvelo M, Rovira C, Piñeiro Á, Garcia-Fandino R. Conde-Torres D, et al. Among authors: rovira c. Comput Struct Biotechnol J. 2024 Apr 12;25:61-74. doi: 10.1016/j.csbj.2024.04.022. eCollection 2024 Dec. Comput Struct Biotechnol J. 2024. PMID: 38695015 Free PMC article.

6

Enzymatic C4-Epimerization of UDP-Glucuronic Acid: Precisely Steered Rotation of a Transient 4-Keto Intermediate for an Inverted Reaction without Decarboxylation.

Borg AJE, Esquivias O, Coines J, Rovira C, Nidetzky B. Borg AJE, et al. Among authors: rovira c. Angew Chem Int Ed Engl. 2023 Jan 23;62(4):e202211937. doi: 10.1002/anie.202211937. Epub 2022 Dec 15. Angew Chem Int Ed Engl. 2023. PMID: 36308301 Free PMC article.

7

Constrained Catalytic Itinerary of a Retaining 3,6-Anhydro-D-Galactosidase, a Key Enzyme in Red Algal Cell Wall Degradation.

Wallace MD, Cuxart I, Roret T, Guée L, Debowski AW, Czjzek M, Rovira C, Stubbs KA, Ficko-Blean E. Wallace MD, et al. Among authors: rovira c. Angew Chem Int Ed Engl. 2024 Oct 21;63(43):e202411171. doi: 10.1002/anie.202411171. Epub 2024 Sep 17. Angew Chem Int Ed Engl. 2024. PMID: 39022920 Free article.

8

An Unusual His/Asp Dyad Operates Catalysis in Agar-Degrading Glycosidases.

Sagiroglugil M, Nin-Hill A, Ficko-Blean E, Rovira C. Sagiroglugil M, et al. Among authors: rovira c. ACS Catal. 2024 Nov 1;14(22):16897-16904. doi: 10.1021/acscatal.4c04139. eCollection 2024 Nov 15. ACS Catal. 2024. PMID: 39569157 Free PMC article.

9

Glycosylium Ions in Superacid Mimic the Transition State of Enzyme Reactions.

Armand M, Nin-Hill A, Ardá A, Berrino E, Désiré J, Martin-Mingot A, Michelet B, Jiménez-Barbero J, Blériot Y, Rovira C, Thibaudeau S. Armand M, et al. Among authors: rovira c. J Am Chem Soc. 2024 Nov 27;146(47):32618-32626. doi: 10.1021/jacs.4c11677. Epub 2024 Nov 13. J Am Chem Soc. 2024. PMID: 39535973

10

TREATMENT OF EARLY-ONSET FETAL GROWTH RESTRICTION WITH LOW MOLECULAR WEIGHT HEPARIN DOES NOT PROLONG GESTATION: A RANDOMIZED CLINICAL TRIAL.

González A, Peguero A, Meler E, Camprubí-Camprubí M, Rovira C, Gomez-Roig MD, Oros D, Ibáñez-Burillo P, Schoorlemmer J, Masoller N, Tàssies MD, Figueras F, Mazarico E. González A, et al. Among authors: rovira c. Am J Obstet Gynecol. 2024 Nov 7:S0002-9378(24)01127-X. doi: 10.1016/j.ajog.2024.10.055. Online ahead of print. Am J Obstet Gynecol. 2024. PMID: 39521297

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