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Synthetic enforcement of STING signaling in cancer cells appropriates the immune microenvironment for checkpoint inhibitor therapy.
Sci Adv. 2023 Mar 17;9(11):eadd8564. doi: 10.1126/sciadv.add8564. Epub 2023 Mar 15.
Sci Adv. 2023.
PMID: 36921054
Free PMC article.
Unrestrained cleavage of Roquin-1 by MALT1 induces spontaneous T cell activation and the development of autoimmunity.
Schmidt H, Raj T, O'Neill TJ, Muschaweckh A, Giesert F, Negraschus A, Hoefig KP, Behrens G, Esser L, Baumann C, Feederle R, Plaza-Sirvent C, Geerlof A, Gewies A, Isay SE, Ruland J, Schmitz I, Wurst W, Korn T, Krappmann D, Heissmeyer V.
Schmidt H, et al. Among authors: isay se.
Proc Natl Acad Sci U S A. 2023 Nov 28;120(48):e2309205120. doi: 10.1073/pnas.2309205120. Epub 2023 Nov 21.
Proc Natl Acad Sci U S A. 2023.
PMID: 37988467
Free PMC article.
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Enforced CARD11/MALT1 signaling in dendritic cells triggers hemophagocytic lymphohistiocytosis.
Isay SE, Vornholz L, Schnalzger T, Groll T, Magg T, Loll P, Weirich G, Steiger K, Hauck F, Ruland J.
Isay SE, et al.
Proc Natl Acad Sci U S A. 2024 Dec 17;121(51):e2413162121. doi: 10.1073/pnas.2413162121. Epub 2024 Dec 11.
Proc Natl Acad Sci U S A. 2024.
PMID: 39661061
Free PMC article.
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Regulation of the Mitochondrion-Fatty Acid Axis for the Metabolic Reprogramming of Chlamydia trachomatis during Treatment with β-Lactam Antimicrobials.
Shima K, Kaufhold I, Eder T, Käding N, Schmidt N, Ogunsulire IM, Deenen R, Köhrer K, Friedrich D, Isay SE, Grebien F, Klinger M, Richer BC, Günther UL, Deepe GS Jr, Rattei T, Rupp J.
Shima K, et al. Among authors: isay se.
mBio. 2021 Mar 30;12(2):e00023-21. doi: 10.1128/mBio.00023-21.
mBio. 2021.
PMID: 33785629
Free PMC article.
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