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14 results

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Abatacept for Delay of Type 1 Diabetes Progression in Stage 1 Relatives at Risk: A Randomized, Double-Masked, Controlled Trial.
Russell WE, Bundy BN, Anderson MS, Cooney LA, Gitelman SE, Goland RS, Gottlieb PA, Greenbaum CJ, Haller MJ, Krischer JP, Libman IM, Linsley PS, Long SA, Lord SM, Moore DJ, Moore WV, Moran AM, Muir AB, Raskin P, Skyler JS, Wentworth JM, Wherrett DK, Wilson DM, Ziegler AG, Herold KC; Type 1 Diabetes TrialNet Study Group. Russell WE, et al. Among authors: cooney la. Diabetes Care. 2023 May 1;46(5):1005-1013. doi: 10.2337/dc22-2200. Diabetes Care. 2023. PMID: 36920087 Free PMC article. Clinical Trial.
A first-in-human, open-label Phase 1b and a randomised, double-blind Phase 2a clinical trial in recent-onset type 1 diabetes with AG019 as monotherapy and in combination with teplizumab.
Mathieu C, Wiedeman A, Cerosaletti K, Long SA, Serti E, Cooney L, Vermeiren J, Caluwaerts S, Van Huynegem K, Steidler L, Blomme S, Rottiers P, Nepom GT, Herold KC; AG019-T1D-101 Trial Investigators. Mathieu C, et al. Diabetologia. 2024 Jan;67(1):27-41. doi: 10.1007/s00125-023-06014-2. Epub 2023 Oct 2. Diabetologia. 2024. PMID: 37782353 Free PMC article. Clinical Trial.
Activation of cytotoxic lymphocytes through CD6 enhances killing of cancer cells.
Gurrea-Rubio M, Wu Q, Amin MA, Tsou PS, Campbell PL, Amarista CI, Ikari Y, Brodie WD, Mattichak MN, Muraoka S, Randon PM, Lind ME, Ruth JH, Mao-Draayer Y, Ding S, Shen X, Cooney LA, Lin F, Fox DA. Gurrea-Rubio M, et al. Among authors: cooney la. Cancer Immunol Immunother. 2024 Jan 27;73(2):34. doi: 10.1007/s00262-023-03578-1. Cancer Immunol Immunother. 2024. PMID: 38280067 Free PMC article.
Activation of Cytotoxic Lymphocytes Through CD6 Enhances Killing of Cancer Cells.
Gurrea-Rubio M, Wu Q, Amin MA, Tsou PS, Campbell PL, Amarista CE, Ikari Y, Brodie WD, Mattichak MN, Muraoka S, Randon PM, Lind ME, Ruth JH, Mao-Draayer Y, Ding S, Shen X, Cooney LA, Lin F, Fox DA. Gurrea-Rubio M, et al. Among authors: cooney la. Res Sq [Preprint]. 2023 Oct 9:rs.3.rs-3405677. doi: 10.21203/rs.3.rs-3405677/v1. Res Sq. 2023. Update in: Cancer Immunol Immunother. 2024 Jan 27;73(2):34. doi: 10.1007/s00262-023-03578-1 PMID: 37886483 Free PMC article. Updated. Preprint.
Immunosuppression causes dynamic changes in expression QTLs in psoriatic skin.
Xiao Q, Mears J, Nathan A, Ishigaki K, Baglaenko Y, Lim N, Cooney LA, Harris KM, Anderson MS, Fox DA, Smilek DE, Krueger JG, Raychaudhuri S. Xiao Q, et al. Among authors: cooney la. Nat Commun. 2023 Oct 7;14(1):6268. doi: 10.1038/s41467-023-41984-2. Nat Commun. 2023. PMID: 37805522 Free PMC article.
Regulation of Th17 maturation by interleukin 4.
Cooney LA, Fox DA. Cooney LA, et al. Crit Rev Immunol. 2013;33(5):379-87. doi: 10.1615/critrevimmunol.2013007096. Crit Rev Immunol. 2013. PMID: 24099299 Review.
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