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QR-313, an Antisense Oligonucleotide, Shows Therapeutic Efficacy for Treatment of Dominant and Recessive Dystrophic Epidermolysis Bullosa: A Preclinical Study.
Bornert O, Hogervorst M, Nauroy P, Bischof J, Swildens J, Athanasiou I, Tufa SF, Keene DR, Kiritsi D, Hainzl S, Murauer EM, Marinkovich MP, Platenburg G, Hausser I, Wally V, Ritsema T, Koller U, Haisma EM, Nyström A. Bornert O, et al. Among authors: bischof j. J Invest Dermatol. 2021 Apr;141(4):883-893.e6. doi: 10.1016/j.jid.2020.08.018. Epub 2020 Sep 16. J Invest Dermatol. 2021. PMID: 32946877 Free article.
A non-viral and selection-free COL7A1 HDR approach with improved safety profile for dystrophic epidermolysis bullosa.
Kocher T, Bischof J, Haas SA, March OP, Liemberger B, Hainzl S, Illmer J, Hoog A, Muigg K, Binder HM, Klausegger A, Strunk D, Bauer JW, Cathomen T, Koller U. Kocher T, et al. Among authors: bischof j. Mol Ther Nucleic Acids. 2021 May 29;25:237-250. doi: 10.1016/j.omtn.2021.05.015. eCollection 2021 Sep 3. Mol Ther Nucleic Acids. 2021. PMID: 34458008 Free PMC article.
Current developments in gene therapy for epidermolysis bullosa.
Kocher T, Petkovic I, Bischof J, Koller U. Kocher T, et al. Among authors: bischof j. Expert Opin Biol Ther. 2022 Sep;22(9):1137-1150. doi: 10.1080/14712598.2022.2049229. Epub 2022 Mar 14. Expert Opin Biol Ther. 2022. PMID: 35235467
Paired nicking-mediated COL17A1 reframing for junctional epidermolysis bullosa.
Bischof J, March OP, Liemberger B, Haas SA, Hainzl S, Petković I, Leb-Reichl V, Illmer J, Korotchenko E, Klausegger A, Hoog A, Binder HM, Garcia M, Duarte B, Strunk D, Larcher F, Reichelt J, Guttmann-Gruber C, Wally V, Hofbauer JP, Bauer JW, Cathomen T, Kocher T, Koller U. Bischof J, et al. Mol Ther. 2022 Aug 3;30(8):2680-2692. doi: 10.1016/j.ymthe.2022.04.020. Epub 2022 Apr 30. Mol Ther. 2022. PMID: 35490295 Free PMC article.
COL17A1 editing via homology-directed repair in junctional epidermolysis bullosa.
Petković I, Bischof J, Kocher T, March OP, Liemberger B, Hainzl S, Strunk D, Raninger AM, Binder HM, Reichelt J, Guttmann-Gruber C, Wally V, Piñón Hofbauer J, Bauer JW, Koller U. Petković I, et al. Among authors: bischof j. Front Med (Lausanne). 2022 Aug 25;9:976604. doi: 10.3389/fmed.2022.976604. eCollection 2022. Front Med (Lausanne). 2022. PMID: 36091706 Free PMC article.
COL7A1 Editing via RNA Trans-Splicing in RDEB-Derived Skin Equivalents.
Liemberger B, Bischof J, Ablinger M, Hainzl S, Murauer EM, Lackner N, Ebner P, Kocher T, Nyström A, Wally V, Mayr E, Guttmann-Gruber C, Hofbauer JP, Bauer JW, Koller U. Liemberger B, et al. Among authors: bischof j. Int J Mol Sci. 2023 Feb 22;24(5):4341. doi: 10.3390/ijms24054341. Int J Mol Sci. 2023. PMID: 36901775 Free PMC article.
MicroRNA-200b-mediated reversion of a spectrum of epithelial-to-mesenchymal transition states in recessive dystrophic epidermolysis bullosa squamous cell carcinomas.
Illmer J, Zauner R, Piñón Hofbauer J, Wimmer M, Gruner S, Ablinger M, Bischof J, Dorfer S, Hainzl S, Tober V, Bergson S, Sarig O, Samuelov L, Guttmann-Gruber C, Shalom-Feuerstein R, Sprecher E, Koller U, Laimer M, Bauer JW, Wally V. Illmer J, et al. Among authors: bischof j. Br J Dermatol. 2023 Dec 20;190(1):80-93. doi: 10.1093/bjd/ljad335. Br J Dermatol. 2023. PMID: 37681509
453 results