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MYC-driven synthesis of Siglec ligands is a glycoimmune checkpoint.
Smith BAH, Deutzmann A, Correa KM, Delaveris CS, Dhanasekaran R, Dove CG, Sullivan DK, Wisnovsky S, Stark JC, Pluvinage JV, Swaminathan S, Riley NM, Rajan A, Majeti R, Felsher DW, Bertozzi CR. Smith BAH, et al. Among authors: swaminathan s. Proc Natl Acad Sci U S A. 2023 Mar 14;120(11):e2215376120. doi: 10.1073/pnas.2215376120. Epub 2023 Mar 10. Proc Natl Acad Sci U S A. 2023. PMID: 36897988 Free PMC article.
BACH2 mediates negative selection and p53-dependent tumor suppression at the pre-B cell receptor checkpoint.
Swaminathan S, Huang C, Geng H, Chen Z, Harvey R, Kang H, Ng C, Titz B, Hurtz C, Sadiyah MF, Nowak D, Thoennissen GB, Rand V, Graeber TG, Koeffler HP, Carroll WL, Willman CL, Hall AG, Igarashi K, Melnick A, Müschen M. Swaminathan S, et al. Nat Med. 2013 Aug;19(8):1014-22. doi: 10.1038/nm.3247. Epub 2013 Jul 14. Nat Med. 2013. PMID: 23852341 Free PMC article.
Mechanistic rationale for targeting the unfolded protein response in pre-B acute lymphoblastic leukemia.
Kharabi Masouleh B, Geng H, Hurtz C, Chan LN, Logan AC, Chang MS, Huang C, Swaminathan S, Sun H, Paietta E, Melnick AM, Koeffler P, Müschen M. Kharabi Masouleh B, et al. Among authors: swaminathan s. Proc Natl Acad Sci U S A. 2014 May 27;111(21):E2219-28. doi: 10.1073/pnas.1400958111. Epub 2014 May 12. Proc Natl Acad Sci U S A. 2014. PMID: 24821775 Free PMC article.
Activated natural killer cells predict poor clinical prognosis in high-risk B- and T-cell acute lymphoblastic leukemia.
Duault C, Kumar A, Taghi Khani A, Lee SJ, Yang L, Huang M, Hurtz C, Manning B, Ghoda L, McDonald T, Lacayo NJ, Sakamoto KM, Carroll M, Tasian SK, Marcucci G, Yu J, Caligiuri MA, Maecker HT, Swaminathan S. Duault C, et al. Among authors: swaminathan s. Blood. 2021 Oct 21;138(16):1465-1480. doi: 10.1182/blood.2020009871. Blood. 2021. PMID: 34077953 Free PMC article.
GM-CSF: A Double-Edged Sword in Cancer Immunotherapy.
Kumar A, Taghi Khani A, Sanchez Ortiz A, Swaminathan S. Kumar A, et al. Among authors: swaminathan s. Front Immunol. 2022 Jul 5;13:901277. doi: 10.3389/fimmu.2022.901277. eCollection 2022. Front Immunol. 2022. PMID: 35865534 Free PMC article. Review.
Isoform-specific knockdown of long and intermediate prolactin receptors interferes with evolution of B-cell neoplasms.
Taghi Khani A, Kumar A, Sanchez Ortiz A, Radecki KC, Aramburo S, Lee SJ, Hu Z, Damirchi B, Lorenson MY, Wu X, Gu Z, Stohl W, Sanz I, Meffre E, Müschen M, Forman SJ, Koff JL, Walker AM, Swaminathan S. Taghi Khani A, et al. Among authors: swaminathan s. Commun Biol. 2023 Mar 20;6(1):295. doi: 10.1038/s42003-023-04667-8. Commun Biol. 2023. PMID: 36941341 Free PMC article.
Metabolic convergence on lipogenesis in RAS, BCR-ABL, and MYC-driven lymphoid malignancies.
Liefwalker DF, Ryan M, Wang Z, Pathak KV, Plaisier S, Shah V, Babra B, Dewson GS, Lai IK, Mosley AR, Fueger PT, Casey SC, Jiang L, Pirrotte P, Swaminathan S, Sears RC. Liefwalker DF, et al. Among authors: swaminathan s. Cancer Metab. 2021 Aug 16;9(1):31. doi: 10.1186/s40170-021-00263-8. Cancer Metab. 2021. PMID: 34399819 Free PMC article.
1,710 results