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A disease-associated XPA allele interferes with TFIIH binding and primarily affects transcription-coupled nucleotide excision repair.
van den Heuvel D, Kim M, Wondergem AP, van der Meer PJ, Witkamp M, Lambregtse F, Kim HS, Kan F, Apelt K, Kragten A, González-Prieto R, Vertegaal ACO, Yeo JE, Kim BG, van Doorn R, Schärer OD, Luijsterburg MS. van den Heuvel D, et al. Among authors: lambregtse f. Proc Natl Acad Sci U S A. 2023 Mar 14;120(11):e2208860120. doi: 10.1073/pnas.2208860120. Epub 2023 Mar 9. Proc Natl Acad Sci U S A. 2023. PMID: 36893274 Free PMC article.
Apolipoprotein L genes are novel mediators of inflammation in beta cells.
Paz-Barba M, Muñoz Garcia A, de Winter TJJ, de Graaf N, van Agen M, van der Sar E, Lambregtse F, Daleman L, van der Slik A, Zaldumbide A, de Koning EJP, Carlotti F. Paz-Barba M, et al. Among authors: lambregtse f. Diabetologia. 2024 Jan;67(1):124-136. doi: 10.1007/s00125-023-06033-z. Epub 2023 Nov 4. Diabetologia. 2024. PMID: 37924378 Free PMC article.