Fang J - Search Results

1

A single F153Sβ3 mutation causes constitutive integrin αIIbβ3 activation in a variant form of Glanzmann thrombasthenia.

Koukouritaki SB, Thinn AMM, Ashworth KJ, Fang J, Slater HS, Du LM, Nguyen HTT, Pillois X, Nurden AT, Ng CJ, Di Paola J, Zhu J, Wilcox DA. Koukouritaki SB, et al. Among authors: fang j. Blood Adv. 2023 Jul 11;7(13):3180-3191. doi: 10.1182/bloodadvances.2022009495. Blood Adv. 2023. PMID: 36884296 Free PMC article.

2

Therapeutic expression of the platelet-specific integrin, alphaIIbbeta3, in a murine model for Glanzmann thrombasthenia.

Fang J, Hodivala-Dilke K, Johnson BD, Du LM, Hynes RO, White GC 2nd, Wilcox DA. Fang J, et al. Blood. 2005 Oct 15;106(8):2671-9. doi: 10.1182/blood-2004-12-4619. Epub 2005 Jun 21. Blood. 2005. PMID: 15972454 Free PMC article.

3

Heparin promotes platelet responsiveness by potentiating αIIbβ3-mediated outside-in signaling.

Gao C, Boylan B, Fang J, Wilcox DA, Newman DK, Newman PJ. Gao C, et al. Among authors: fang j. Blood. 2011 May 5;117(18):4946-52. doi: 10.1182/blood-2010-09-307751. Epub 2011 Mar 2. Blood. 2011. PMID: 21368290 Free PMC article.

4

Platelet gene therapy improves hemostatic function for integrin alphaIIbbeta3-deficient dogs.

Fang J, Jensen ES, Boudreaux MK, Du LM, Hawkins TB, Koukouritaki SB, Cornetta K, Wilcox DA. Fang J, et al. Proc Natl Acad Sci U S A. 2011 Jun 7;108(23):9583-8. doi: 10.1073/pnas.1016394108. Epub 2011 May 23. Proc Natl Acad Sci U S A. 2011. PMID: 21606353 Free PMC article.

5

C560Rβ3 caused platelet integrin αII b β3 to bind fibrinogen continuously, but resulted in a severe bleeding syndrome and increased murine mortality.

Fang J, Nurden P, North P, Nurden AT, Du LM, Valentin N, Wilcox DA. Fang J, et al. J Thromb Haemost. 2013 Jun;11(6):1163-71. doi: 10.1111/jth.12209. J Thromb Haemost. 2013. PMID: 23551977 Free PMC article.

6

Platelet-targeted gene therapy with human factor VIII establishes haemostasis in dogs with haemophilia A.

Du LM, Nurden P, Nurden AT, Nichols TC, Bellinger DA, Jensen ES, Haberichter SL, Merricks E, Raymer RA, Fang J, Koukouritaki SB, Jacobi PM, Hawkins TB, Cornetta K, Shi Q, Wilcox DA. Du LM, et al. Among authors: fang j. Nat Commun. 2013;4:2773. doi: 10.1038/ncomms3773. Nat Commun. 2013. PMID: 24253479 Free PMC article.

7

Thromboelastometry assessment of hemostatic properties in various murine models with coagulopathy and the effect of factor VIII therapeutics.

Schroeder JA, Kuether EA, Fang J, Jing W, Weiler H, Wilcox DA, Montgomery RR, Shi Q. Schroeder JA, et al. Among authors: fang j. J Thromb Haemost. 2021 Oct;19(10):2417-2427. doi: 10.1111/jth.15456. Epub 2021 Jul 23. J Thromb Haemost. 2021. PMID: 34245090 Free PMC article.

8

In vivo enrichment of genetically manipulated platelets corrects the murine hemophilic phenotype and induces immune tolerance even using a low multiplicity of infection.

Schroeder JA, Chen Y, Fang J, Wilcox DA, Shi Q. Schroeder JA, et al. Among authors: fang j. J Thromb Haemost. 2014 Aug;12(8):1283-93. doi: 10.1111/jth.12633. Epub 2014 Jul 17. J Thromb Haemost. 2014. PMID: 24931217 Free PMC article.

9

Lentivirus-mediated platelet-derived factor VIII gene therapy in murine haemophilia A.

Shi Q, Wilcox DA, Fahs SA, Fang J, Johnson BD, DU LM, Desai D, Montgomery RR. Shi Q, et al. Among authors: fang j. J Thromb Haemost. 2007 Feb;5(2):352-61. doi: 10.1111/j.1538-7836.2007.02346.x. J Thromb Haemost. 2007. PMID: 17269937 Free article.

10

Arachidonic acid-induced dilation in human coronary arterioles: convergence of signaling mechanisms on endothelial TRPV4-mediated Ca2+ entry.

Zheng X, Zinkevich NS, Gebremedhin D, Gauthier KM, Nishijima Y, Fang J, Wilcox DA, Campbell WB, Gutterman DD, Zhang DX. Zheng X, et al. Among authors: fang j. J Am Heart Assoc. 2013 Apr 25;2(3):e000080. doi: 10.1161/JAHA.113.000080. J Am Heart Assoc. 2013. PMID: 23619744 Free PMC article.

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