Ashworth KJ - Search Results

1

A single F153Sβ3 mutation causes constitutive integrin αIIbβ3 activation in a variant form of Glanzmann thrombasthenia.

Koukouritaki SB, Thinn AMM, Ashworth KJ, Fang J, Slater HS, Du LM, Nguyen HTT, Pillois X, Nurden AT, Ng CJ, Di Paola J, Zhu J, Wilcox DA. Koukouritaki SB, et al. Among authors: ashworth kj. Blood Adv. 2023 Jul 11;7(13):3180-3191. doi: 10.1182/bloodadvances.2022009495. Blood Adv. 2023. PMID: 36884296 Free PMC article.

2

Evaluation of a microfluidic flow assay to screen for von Willebrand disease and low von Willebrand factor levels.

Lehmann M, Ashworth K, Manco-Johnson M, Di Paola J, Neeves KB, Ng CJ. Lehmann M, et al. J Thromb Haemost. 2018 Jan;16(1):104-115. doi: 10.1111/jth.13881. Epub 2017 Nov 23. J Thromb Haemost. 2018. PMID: 29064615 Free PMC article.

3

Effects of anti-β2GPI antibodies on VWF release from human umbilical vein endothelial cells and ADAMTS13 activity.

Ng CJ, McCrae KR, Ashworth K, Sosa LJ, Betapudi V, Manco-Johnson MJ, Liu A, Dong JF, Chung D, White-Adams TC, López JA, Di Paola J. Ng CJ, et al. Res Pract Thromb Haemost. 2018 Mar 24;2(2):380-389. doi: 10.1002/rth2.12090. eCollection 2018 Apr. Res Pract Thromb Haemost. 2018. PMID: 30046742 Free PMC article.

4

Turbulent Flow Promotes Cleavage of VWF (von Willebrand Factor) by ADAMTS13 (A Disintegrin and Metalloproteinase With a Thrombospondin Type-1 Motif, Member 13).

Bortot M, Ashworth K, Sharifi A, Walker F, Crawford NC, Neeves KB, Bark D Jr, Di Paola J. Bortot M, et al. Arterioscler Thromb Vasc Biol. 2019 Sep;39(9):1831-1842. doi: 10.1161/ATVBAHA.119.312814. Epub 2019 Jul 11. Arterioscler Thromb Vasc Biol. 2019. PMID: 31291760 Free PMC article.

5

TNF-α-driven inflammation and mitochondrial dysfunction define the platelet hyperreactivity of aging.

Davizon-Castillo P, McMahon B, Aguila S, Bark D, Ashworth K, Allawzi A, Campbell RA, Montenont E, Nemkov T, D'Alessandro A, Clendenen N, Shih L, Sanders NA, Higa K, Cox A, Padilla-Romo Z, Hernandez G, Wartchow E, Trahan GD, Nozik-Grayck E, Jones K, Pietras EM, DeGregori J, Rondina MT, Di Paola J. Davizon-Castillo P, et al. Blood. 2019 Aug 29;134(9):727-740. doi: 10.1182/blood.2019000200. Epub 2019 Jul 16. Blood. 2019. PMID: 31311815 Free PMC article.

6

Platelet α-granules are required for occlusive high-shear-rate thrombosis.

Kim DA, Ashworth KJ, Di Paola J, Ku DN. Kim DA, et al. Among authors: ashworth kj. Blood Adv. 2020 Jul 28;4(14):3258-3267. doi: 10.1182/bloodadvances.2020002117. Blood Adv. 2020. PMID: 32697818 Free PMC article.

7

Pathologic Shear and Elongation Rates Do Not Cause Cleavage of Von Willebrand Factor by ADAMTS13 in a Purified System.

Bortot M, Sharifi A, Ashworth K, Walker F, Cox A, Ruegg K, Clendenen N, Neeves KB, Bark D Jr, Di Paola J. Bortot M, et al. Cell Mol Bioeng. 2020 Jul 17;13(4):379-390. doi: 10.1007/s12195-020-00631-2. eCollection 2020 Aug. Cell Mol Bioeng. 2020. PMID: 32952737 Free PMC article.

8

Negatively charged nanoparticles of multiple materials inhibit shear-induced platelet accumulation.

Griffin MT, Ashworth K, Hill N, von Behren J, Di Paola J, Ku DN. Griffin MT, et al. Nanomedicine. 2021 Jul;35:102405. doi: 10.1016/j.nano.2021.102405. Epub 2021 Apr 28. Nanomedicine. 2021. PMID: 33932591

9

Single-cell transcriptional analysis of human endothelial colony-forming cells from patients with low VWF levels.

Ng CJ, Liu A, Venkataraman S, Ashworth KJ, Baker CD, O'Rourke R, Vibhakar R, Jones KL, Di Paola J. Ng CJ, et al. Among authors: ashworth kj. Blood. 2022 Apr 7;139(14):2240-2251. doi: 10.1182/blood.2021010683. Blood. 2022. PMID: 35143643 Free PMC article.

10

SVEP1 is an endogenous ligand for the orphan receptor PEAR1.

Elenbaas JS, Pudupakkam U, Ashworth KJ, Kang CJ, Patel V, Santana K, Jung IH, Lee PC, Burks KH, Amrute JM, Mecham RP, Halabi CM, Alisio A, Di Paola J, Stitziel NO. Elenbaas JS, et al. Among authors: ashworth kj. Nat Commun. 2023 Feb 15;14(1):850. doi: 10.1038/s41467-023-36486-0. Nat Commun. 2023. PMID: 36792666 Free PMC article.

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