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Carboxylesterase 1 family knockout alters drug disposition and lipid metabolism.
Gan C, Wang J, Martínez-Chávez A, Hillebrand M, de Vries N, Beukers J, Wagenaar E, Wang Y, Lebre MC, Rosing H, Klarenbeek S, Ali RB, Pritchard C, Huijbers I, Beijnen JH, Schinkel AH. Gan C, et al. Among authors: huijbers i. Acta Pharm Sin B. 2023 Feb;13(2):618-631. doi: 10.1016/j.apsb.2022.10.017. Epub 2022 Oct 25. Acta Pharm Sin B. 2023. PMID: 36873183 Free PMC article.
Minimal tolerance to a tumor antigen encoded by a cancer-germline gene.
Huijbers IJ, Soudja SM, Uyttenhove C, Buferne M, Inderberg-Suso EM, Colau D, Pilotte L, Powis de Tenbossche CG, Chomez P, Brasseur F, Schmitt-Verhulst AM, Van den Eynde BJ. Huijbers IJ, et al. J Immunol. 2012 Jan 1;188(1):111-21. doi: 10.4049/jimmunol.1002612. Epub 2011 Dec 2. J Immunol. 2012. PMID: 22140254
An inducible mouse model of melanoma expressing a defined tumor antigen.
Huijbers IJ, Krimpenfort P, Chomez P, van der Valk MA, Song JY, Inderberg-Suso EM, Schmitt-Verhulst AM, Berns A, Van den Eynde BJ. Huijbers IJ, et al. Cancer Res. 2006 Mar 15;66(6):3278-86. doi: 10.1158/0008-5472.CAN-05-3216. Cancer Res. 2006. PMID: 16540681 Free article.
Selective resistance to the PARP inhibitor olaparib in a mouse model for BRCA1-deficient metaplastic breast cancer.
Henneman L, van Miltenburg MH, Michalak EM, Braumuller TM, Jaspers JE, Drenth AP, de Korte-Grimmerink R, Gogola E, Szuhai K, Schlicker A, Bin Ali R, Pritchard C, Huijbers IJ, Berns A, Rottenberg S, Jonkers J. Henneman L, et al. Proc Natl Acad Sci U S A. 2015 Jul 7;112(27):8409-14. doi: 10.1073/pnas.1500223112. Epub 2015 Jun 22. Proc Natl Acad Sci U S A. 2015. PMID: 26100884 Free PMC article.
Using the GEMM-ESC strategy to study gene function in mouse models.
Huijbers IJ, Del Bravo J, Bin Ali R, Pritchard C, Braumuller TM, van Miltenburg MH, Henneman L, Michalak EM, Berns A, Jonkers J. Huijbers IJ, et al. Nat Protoc. 2015 Nov;10(11):1755-85. doi: 10.1038/nprot.2015.114. Epub 2015 Oct 15. Nat Protoc. 2015. PMID: 26492136
45 results