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The value of post-operative chemotherapy after chemoradiotherapy in patients with high-risk locally advanced rectal cancer-results from the RAPIDO trial.
Dijkstra EA, Zwart WH, Nilsson PJ, Putter H, Roodvoets AGH, Meershoek-Klein Kranenbarg E, Frödin JE, Nygren P, Østergaard L, Kersten C, Verbiené I, Cervantes A, Hendriks MP, Capdevila J, Edhemovic I, van de Velde CJH, Marijnen CAM, van Etten B, Hospers GAP, Glimelius B; collaborative investigators. Dijkstra EA, et al. Among authors: nygren p. ESMO Open. 2023 Apr;8(2):101158. doi: 10.1016/j.esmoop.2023.101158. Epub 2023 Mar 3. ESMO Open. 2023. PMID: 36871393 Free PMC article. Clinical Trial.
Caprin-1 binding to the critical stress granule protein G3BP1 is influenced by pH.
Schulte T, Panas MD, Han X, Williams L, Kedersha N, Fleck JS, Tan TJC, Dopico XC, Olsson A, Morro AM, Hanke L, Nilvebrant J, Giang KA, Nygren PÅ, Anderson P, Achour A, McInerney GM. Schulte T, et al. Among authors: nygren pa. Open Biol. 2023 May;13(5):220369. doi: 10.1098/rsob.220369. Epub 2023 May 10. Open Biol. 2023. PMID: 37161291 Free PMC article.
High-throughput drug screening identifies SMAC mimetics as enhancers of NK cell cytotoxicity in chronic myeloid leukemia.
Nygren PJ, Bouhlal JOV, Jokinen E, Forstén S, Laajala E, Dias DAA, Adnan Awad S, Ianevski A, Klievink J, Lähteenmäki H, Kuusanmäki H, Myllymäki M, Kasanen T, Saeed K, Lee DA, Flagship I, Hjorth-Hansen H, Aittokallio T, Dufva O, Mustjoki S. Nygren PJ, et al. Blood. 2025 Jan 10:blood.2024025286. doi: 10.1182/blood.2024025286. Online ahead of print. Blood. 2025. PMID: 39792962
Lecanemab demonstrates highly selective binding to Aβ protofibrils isolated from Alzheimer's disease brains.
Johannesson M, Söderberg L, Zachrisson O, Fritz N, Kylefjord H, Gkanatsiou E, Button E, Svensson AS, Rachalski A, Nygren P, Osswald G, Lannfelt L, Möller C. Johannesson M, et al. Among authors: nygren p. Mol Cell Neurosci. 2024 Sep;130:103949. doi: 10.1016/j.mcn.2024.103949. Epub 2024 Jun 20. Mol Cell Neurosci. 2024. PMID: 38906341 Free article.
Disease modifying effects of the amyloid-beta protofibril-selective antibody mAb158 in aged Tg2576 transgenic mice.
Rizoska B, Zachrisson O, Appelkvist P, Boström E, Björklund M, Rachalski A, Gkanatsiou E, Kylefjord H, Söderberg L, Nygren P, Eriksson F, Ishikawa Y, Fukushima T, Koyama A, Osswald G, Lannfelt L, Möller C. Rizoska B, et al. Among authors: nygren p. Mol Cell Neurosci. 2024 Sep;130:103950. doi: 10.1016/j.mcn.2024.103950. Epub 2024 Jun 18. Mol Cell Neurosci. 2024. PMID: 38901655 Free article.
Site-directed conjugation of single-stranded DNA to affinity proteins: quantifying the importance of conjugation strategy.
Rocha Tapia A, Abgottspon F, Nilvebrant J, Nygren PÅ, Duclos Ivetich S, Bello Hernandez AJ, Thanasi IA, Szijj PA, Sekkat G, Cuenot FM, Chudasama V, Aceto N, deMello AJ, Richards DA. Rocha Tapia A, et al. Among authors: nygren pa. Chem Sci. 2024 May 7;15(23):8982-8992. doi: 10.1039/d4sc01838a. eCollection 2024 Jun 12. Chem Sci. 2024. PMID: 38873052 Free PMC article.
PCM4EU and PRIME-ROSE: Collaboration for implementation of precision cancer medicine in Europe.
Taskén K, F Haj Mohammad S, Fagereng GL, Sørum Falk R, Helland Å, Barjesteh van Waalwijk van Doorn-Khosrovani S, Steen Carlsson K, Ryll B, Jalkanen K, Edsjö A, Russnes HG, Lassen U, Hallersjö Hult E, Lugowska I, Blay JY, Verlingue L, Abel E, Lowery MA, Krebs MG, Staal Rohrberg K, Ojamaa K, Oliveira J, Verheul HMW, Voest EE, Gelderblom H; PRIME-ROSE Consortium and the PCM4EU Consortium. Taskén K, et al. Acta Oncol. 2024 May 23;63:385-391. doi: 10.2340/1651-226X.2024.34791. Acta Oncol. 2024. PMID: 38779910 Free PMC article.
478 results