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Page 1
Interferon-induced IL-10 drives systemic T-cell dysfunction during chronic liver injury.
Hackstein CP, Spitzer J, Symeonidis K, Horvatic H, Bedke T, Steglich B, Klein S, Assmus LM, Odainic A, Szlapa J, Kessler N, Beyer M, Schmithausen R, Latz E, Flavell RA, Garbi N, Kurts C, Kümmerer BM, Trebicka J, Roers A, Huber S, Schmidt SV, Knolle PA, Abdullah Z. Hackstein CP, et al. Among authors: latz e. J Hepatol. 2023 Jul;79(1):150-166. doi: 10.1016/j.jhep.2023.02.026. Epub 2023 Mar 2. J Hepatol. 2023. PMID: 36870611 Free article.
Systematic assessment of COVID-19 host genetics using whole genome sequencing data.
Schmidt A, Casadei N, Brand F, Demidov G, Vojgani E, Abolhassani A, Aldisi R, Butler-Laporte G; DeCOI host genetics group; Alawathurage TM, Augustin M, Bals R, Bellinghausen C, Berger MM, Bitzer M, Bode C, Boos J, Brenner T, Cornely OA, Eggermann T, Erber J, Feldt T, Fuchsberger C, Gagneur J, Göpel S, Haack T, Häberle H, Hanses F, Heggemann J, Hehr U, Hellmuth JC, Herr C, Hinney A, Hoffmann P, Illig T, Jensen BO, Keitel V, Kim-Hellmuth S, Koehler P, Kurth I, Lanz AL, Latz E, Lehmann C, Luedde T, Maj C, Mian M, Miller A, Muenchhoff M, Pink I, Protzer U, Rohn H, Rybniker J, Scaggiante F, Schaffeldt A, Scherer C, Schieck M, Schmidt SV, Schommers P, Spinner CD, Vehreschild MJGT, Velavan TP, Volland S, Wilfling S, Winter C, Richards JB; DeCOI; Heimbach A, Becker K, Ossowski S, Schultze JL, Nürnberg P, Nöthen MM, Motameny S, Nothnagel M, Riess O, Schulte EC, Ludwig KU. Schmidt A, et al. Among authors: latz e. PLoS Pathog. 2024 Dec 23;20(12):e1012786. doi: 10.1371/journal.ppat.1012786. Online ahead of print. PLoS Pathog. 2024. PMID: 39715278 Free PMC article.
Butyrate and propionate are microbial danger signals that activate the NLRP3 inflammasome in human macrophages upon TLR stimulation.
Wang W, Dernst A, Martin B, Lorenzi L, Cadefau-Fabregat M, Phulphagar K, Wagener A, Budden C, Stair N, Wagner T, Färber H, Jaensch A, Stahl R, Duthie F, Schmidt SV, Coll RC, Meissner F, Cuartero S, Latz E, Mangan MSJ. Wang W, et al. Among authors: latz e. Cell Rep. 2024 Sep 24;43(9):114736. doi: 10.1016/j.celrep.2024.114736. Epub 2024 Sep 13. Cell Rep. 2024. PMID: 39277863 Free article.
From Planning Stage Towards FAIR Data: A Practical Metadatasheet For Biomedical Scientists.
Seep L, Grein S, Splichalova I, Ran D, Mikhael M, Hildebrand S, Lauterbach M, Hiller K, Ribeiro DJS, Sieckmann K, Kardinal R, Huang H, Yu J, Kallabis S, Behrens J, Till A, Peeva V, Strohmeyer A, Bruder J, Blum T, Soriano-Arroquia A, Tischer D, Kuellmer K, Li Y, Beyer M, Gellner AK, Fromme T, Wackerhage H, Klingenspor M, Fenske WK, Scheja L, Meissner F, Schlitzer A, Mass E, Wachten D, Latz E, Pfeifer A, Hasenauer J. Seep L, et al. Among authors: latz e. Sci Data. 2024 May 22;11(1):524. doi: 10.1038/s41597-024-03349-2. Sci Data. 2024. PMID: 38778016 Free PMC article.
Retention of ES cell-derived 129S genome drives NLRP1 hypersensitivity and transcriptional deregulation in Nlrp3tm1Flv mice.
Weiss FD, Alvarez Y, Shakeri F, Sahu A, Leka P, Dernst A, Rollheiser J, Vasconcelos M, Geraci A, Duthie F, Stahl R, Lee HE, Gellner AK, Buness A, Latz E, Meissner F. Weiss FD, et al. Among authors: latz e. Cell Death Differ. 2024 Dec;31(12):1717-1729. doi: 10.1038/s41418-024-01379-2. Epub 2024 Sep 17. Cell Death Differ. 2024. PMID: 39289506 Free PMC article.
Potential of Nucleic Acid Receptor Ligands to Improve Vaccination Efficacy against the Filarial Nematode Litomosoides sigmodontis.
Scheunemann JF, Risch F, Reichwald JJ, Lenz B, Neumann AL, Garbe S, Frohberger SJ, Koschel M, Ajendra J, Rothe M, Latz E, Coch C, Hartmann G, Schumak B, Hoerauf A, Hübner MP. Scheunemann JF, et al. Among authors: latz e. Vaccines (Basel). 2023 May 10;11(5):966. doi: 10.3390/vaccines11050966. Vaccines (Basel). 2023. PMID: 37243070 Free PMC article.
Serum IL-6, sAXL, and YKL-40 as systemic correlates of reduced brain structure and function in Alzheimer's disease: results from the DELCODE study.
Brosseron F, Maass A, Kleineidam L, Ravichandran KA, Kolbe CC, Wolfsgruber S, Santarelli F, Häsler LM, McManus R, Ising C, Röske S, Peters O, Cosma NC, Schneider LS, Wang X, Priller J, Spruth EJ, Altenstein S, Schneider A, Fliessbach K, Wiltfang J, Schott BH, Buerger K, Janowitz D, Dichgans M, Perneczky R, Rauchmann BS, Teipel S, Kilimann I, Görß D, Laske C, Munk MH, Düzel E, Yakupow R, Dobisch L, Metzger CD, Glanz W, Ewers M, Dechent P, Haynes JD, Scheffler K, Roy N, Rostamzadeh A, Spottke A, Ramirez A, Mengel D, Synofzik M, Jucker M, Latz E, Jessen F, Wagner M, Heneka MT; DELCODE study group. Brosseron F, et al. Among authors: latz e. Alzheimers Res Ther. 2023 Jan 12;15(1):13. doi: 10.1186/s13195-022-01118-0. Alzheimers Res Ther. 2023. PMID: 36631909 Free PMC article.
NLRP3 inflammasome signalling in Alzheimer's disease.
McManus RM, Latz E. McManus RM, et al. Among authors: latz e. Neuropharmacology. 2024 Jul 1;252:109941. doi: 10.1016/j.neuropharm.2024.109941. Epub 2024 Mar 31. Neuropharmacology. 2024. PMID: 38565393 Free article. Review.
Topical application of a CCL22-binding aptamer suppresses contact allergy.
Jonczyk A, Gottschalk M, Mangan MSJ, Majlesain Y, Thiem MW, Burbaum LC, Weighardt H, Latz E, Mayer G, Förster I. Jonczyk A, et al. Among authors: latz e. Mol Ther Nucleic Acids. 2024 Jun 17;35(3):102254. doi: 10.1016/j.omtn.2024.102254. eCollection 2024 Sep 10. Mol Ther Nucleic Acids. 2024. PMID: 39071952 Free PMC article.
PLCG2 protective variant p.P522R modulates tau pathology and disease progression in patients with mild cognitive impairment.
Kleineidam L, Chouraki V, Próchnicki T, van der Lee SJ, Madrid-Márquez L, Wagner-Thelen H, Karaca I, Weinhold L, Wolfsgruber S, Boland A, Martino Adami PV, Lewczuk P, Popp J, Brosseron F, Jansen IE, Hulsman M, Kornhuber J, Peters O, Berr C, Heun R, Frölich L, Tzourio C, Dartigues JF, Hüll M, Espinosa A, Hernández I, de Rojas I, Orellana A, Valero S, Stringa N, van Schoor NM, Huisman M, Scheltens P; Alzheimer’s Disease Neuroimaging Initiative (ADNI); Rüther E, Deleuze JF, Wiltfang J, Tarraga L, Schmid M, Scherer M, Riedel-Heller S, Heneka MT, Amouyel P, Jessen F, Boada M, Maier W, Schneider A, González-Pérez A, van der Flier WM, Wagner M, Lambert JC, Holstege H, Sáez ME, Latz E, Ruiz A, Ramirez A. Kleineidam L, et al. Among authors: latz e. Acta Neuropathol. 2020 Jun;139(6):1025-1044. doi: 10.1007/s00401-020-02138-6. Epub 2020 Mar 12. Acta Neuropathol. 2020. PMID: 32166339 Free PMC article.
338 results