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Randomised, placebo-controlled trial and meta-analysis show benefit of ondansetron for irritable bowel syndrome with diarrhoea: The TRITON trial.
Gunn D, Topan R, Barnard L, Fried R, Holloway I, Brindle R, Corsetti M, Scott M, Farmer A, Kapur K, Sanders D, Eugenicos M, Trudgill N, Whorwell P, Mclaughlin J, Akbar A, Houghton L, Dinning PG, Aziz Q, Ford AC, Farrin AJ, Spiller R. Gunn D, et al. Aliment Pharmacol Ther. 2023 Jun;57(11):1258-1271. doi: 10.1111/apt.17426. Epub 2023 Mar 3. Aliment Pharmacol Ther. 2023. PMID: 36866724 Free article.
Abnormalities of mucosal serotonin metabolism and 5-HT3 receptor subunit 3C polymorphism in irritable bowel syndrome with diarrhoea predict responsiveness to ondansetron.
Gunn D, Garsed K, Lam C, Singh G, Lingaya M, Wahl V, Niesler B, Henry A, Hall IP, Whorwell P, Spiller R. Gunn D, et al. Aliment Pharmacol Ther. 2019 Sep;50(5):538-546. doi: 10.1111/apt.15420. Epub 2019 Jul 24. Aliment Pharmacol Ther. 2019. PMID: 31342534 Free PMC article. Clinical Trial.
Treatment of irritable bowel syndrome with diarrhoea using titrated ondansetron (TRITON): study protocol for a randomised controlled trial.
Gunn D, Fried R, Lalani R, Farrin A, Holloway I, Morris T, Olivier C, Kearns R, Corsetti M, Scott M, Farmer A, Emmanuel A, Whorwell P, Yiannakou Y, Sanders D, Mclaughlin J, Kapur K, Eugenicos M, Akbar A, Trudgill N, Houghton L, Dinning PG, Ford AC, Aziz Q, Spiller R. Gunn D, et al. Trials. 2019 Aug 20;20(1):517. doi: 10.1186/s13063-019-3562-6. Trials. 2019. PMID: 31429811 Free PMC article.
Contrasting effects of viscous and particulate fibers on colonic fermentation in vitro and in vivo, and their impact on intestinal water studied by MRI in a randomized trial.
Gunn D, Murthy R, Major G, Wilkinson-Smith V, Hoad C, Marciani L, Remes-Troche J, Gill S, Rossi M, Harris H, Ahn-Jarvis J, Warren F, Whelan K, Spiller R. Gunn D, et al. Am J Clin Nutr. 2020 Sep 1;112(3):595-602. doi: 10.1093/ajcn/nqaa173. Am J Clin Nutr. 2020. PMID: 32619212 Free article. Clinical Trial.
Chronic diarrhoea in adults: what not to miss.
Major GAD, Gunn D. Major GAD, et al. Among authors: gunn d. Curr Opin Gastroenterol. 2019 May;35(3):206-212. doi: 10.1097/MOG.0000000000000516. Curr Opin Gastroenterol. 2019. PMID: 30883385 Review.
224 results