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Pharmacological targeting of MYC-regulated IRE1/XBP1 pathway suppresses MYC-driven breast cancer.
Zhao N, Cao J, Xu L, Tang Q, Dobrolecki LE, Lv X, Talukdar M, Lu Y, Wang X, Hu DZ, Shi Q, Xiang Y, Wang Y, Liu X, Bu W, Jiang Y, Li M, Gong Y, Sun Z, Ying H, Yuan B, Lin X, Feng XH, Hartig SM, Li F, Shen H, Chen Y, Han L, Zeng Q, Patterson JB, Kaipparettu BA, Putluri N, Sicheri F, Rosen JM, Lewis MT, Chen X. Zhao N, et al. Among authors: xu l. J Clin Invest. 2018 Apr 2;128(4):1283-1299. doi: 10.1172/JCI95873. Epub 2018 Feb 26. J Clin Invest. 2018. PMID: 29480818 Free PMC article.
Endoplasmic Reticulum Stress in Bone Metastases.
Xu L, Zhang W, Zhang XH, Chen X. Xu L, et al. Front Oncol. 2020 Jul 24;10:1100. doi: 10.3389/fonc.2020.01100. eCollection 2020. Front Oncol. 2020. PMID: 32850317 Free PMC article. Review.
Protein quality control through endoplasmic reticulum-associated degradation maintains haematopoietic stem cell identity and niche interactions.
Xu L, Liu X, Peng F, Zhang W, Zheng L, Ding Y, Gu T, Lv K, Wang J, Ortinau L, Hu T, Shi X, Shi G, Shang G, Sun S, Iwawaki T, Ji Y, Li W, Rosen JM, Zhang XH, Park D, Adoro S, Catic A, Tong W, Qi L, Nakada D, Chen X. Xu L, et al. Nat Cell Biol. 2020 Oct;22(10):1162-1169. doi: 10.1038/s41556-020-00581-x. Epub 2020 Sep 21. Nat Cell Biol. 2020. PMID: 32958856 Free PMC article.
Development of a RIPK1 degrader to enhance antitumor immunity.
Yu X, Lu D, Qi X, Paudel RR, Lin H, Holloman BL, Jin F, Xu L, Ding L, Peng W, Wang MC, Chen X, Wang J. Yu X, et al. Among authors: xu l. Nat Commun. 2024 Dec 16;15(1):10683. doi: 10.1038/s41467-024-55006-2. Nat Commun. 2024. PMID: 39681571 Free PMC article.
Bone Metastasis Initiation Is Coupled with Bone Remodeling through Osteogenic Differentiation of NG2+ Cells.
Zhang W, Xu Z, Hao X, He T, Li J, Shen Y, Liu K, Gao Y, Liu J, Edwards DG, Muscarella AM, Wu L, Yu L, Xu L, Chen X, Wu YH, Bado IL, Ding Y, Aguirre S, Wang H, Gugala Z, Satcher RL, Wong STC, Zhang XH. Zhang W, et al. Among authors: xu l, xu z. Cancer Discov. 2023 Feb 6;13(2):474-495. doi: 10.1158/2159-8290.CD-22-0220. Cancer Discov. 2023. PMID: 36287038 Free PMC article.
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