Wei Y - Search Results

1

CRISPR/Cas9 screen uncovers functional translation of cryptic lncRNA-encoded open reading frames in human cancer.

Zheng C, Wei Y, Zhang P, Xu L, Zhang Z, Lin K, Hou J, Lv X, Ding Y, Chiu Y, Jain A, Islam N, Malovannaya A, Wu Y, Ding F, Xu H, Sun M, Chen X, Chen Y. Zheng C, et al. Among authors: wei y. J Clin Invest. 2023 Mar 1;133(5):e159940. doi: 10.1172/JCI159940. J Clin Invest. 2023. PMID: 36856111 Free PMC article.

2

GuidePro: a multi-source ensemble predictor for prioritizing sgRNAs in CRISPR/Cas9 protein knockouts.

He W, Wang H, Wei Y, Jiang Z, Tang Y, Chen Y, Xu H. He W, et al. Among authors: wei y. Bioinformatics. 2021 Apr 9;37(1):134-136. doi: 10.1093/bioinformatics/btaa1068. Bioinformatics. 2021. PMID: 33394026 Free PMC article.

3

Qki activates Srebp2-mediated cholesterol biosynthesis for maintenance of eye lens transparency.

Shin S, Zhou H, He C, Wei Y, Wang Y, Shingu T, Zeng A, Wang S, Zhou X, Li H, Zhang Q, Mo Q, Long J, Lan F, Chen Y, Hu J. Shin S, et al. Among authors: wei y. Nat Commun. 2021 May 21;12(1):3005. doi: 10.1038/s41467-021-22782-0. Nat Commun. 2021. PMID: 34021134 Free PMC article.

4

Systematic functional interrogation of human pseudogenes using CRISPRi.

Sun M, Wang Y, Zheng C, Wei Y, Hou J, Zhang P, He W, Lv X, Ding Y, Liang H, Hon CC, Chen X, Xu H, Chen Y. Sun M, et al. Among authors: wei y. Genome Biol. 2021 Aug 23;22(1):240. doi: 10.1186/s13059-021-02464-2. Genome Biol. 2021. PMID: 34425866 Free PMC article.

5

Integrated multi-omics analyses identify key anti-viral host factors and pathways controlling SARS-CoV-2 infection.

Hou J, Wei Y, Zou J, Jaffery R, Liang S, Zheng C, Chen K, Shi PY, Chen Y, Xie X, Peng W. Hou J, et al. Among authors: wei y. Res Sq [Preprint]. 2022 Aug 15:rs.3.rs-1910932. doi: 10.21203/rs.3.rs-1910932/v1. Res Sq. 2022. Update in: Nat Commun. 2024 Jan 2;15(1):109. doi: 10.1038/s41467-023-44175-1 PMID: 36032971 Free PMC article. Updated. Preprint.

6

Critical role of lncEPAT in coupling dysregulated EGFR pathway and histone H2A deubiquitination during glioblastoma tumorigenesis.

Li L, Zhou A, Wei Y, Liu F, Li P, Fang R, Ma L, Zhang S, Wang L, Liu J, Richard HT, Chen Y, Wang H, Huang S. Li L, et al. Among authors: wei y. Sci Adv. 2022 Oct 7;8(40):eabn2571. doi: 10.1126/sciadv.abn2571. Epub 2022 Oct 5. Sci Adv. 2022. PMID: 36197973 Free PMC article.

7

Single-cell CRISPR immune screens reveal immunological roles of tumor intrinsic factors.

Hou J, Liang S, Xu C, Wei Y, Wang Y, Tan Y, Sahni N, McGrail DJ, Bernatchez C, Davies M, Li Y, Chen R, Yi SS, Chen Y, Yee C, Chen K, Peng W. Hou J, et al. Among authors: wei y. NAR Cancer. 2022 Dec 9;4(4):zcac038. doi: 10.1093/narcan/zcac038. eCollection 2022 Dec. NAR Cancer. 2022. PMID: 36518525 Free PMC article.

8

Multiomics analyses reveal DARS1-AS1/YBX1-controlled posttranscriptional circuits promoting glioblastoma tumorigenesis/radioresistance.

Zheng C, Wei Y, Zhang Q, Sun M, Wang Y, Hou J, Zhang P, Lv X, Su D, Jiang Y, Gumin J, Sahni N, Hu B, Wang W, Chen X, McGrail DJ, Zhang C, Huang S, Xu H, Chen J, Lang FF, Hu J, Chen Y. Zheng C, et al. Among authors: wei y. Sci Adv. 2023 Aug 4;9(31):eadf3984. doi: 10.1126/sciadv.adf3984. Epub 2023 Aug 4. Sci Adv. 2023. PMID: 37540752 Free PMC article.

9

CRISPR-Cas9-based functional interrogation of unconventional translatome reveals human cancer dependency on cryptic non-canonical open reading frames.

Zheng C, Wei Y, Zhang P, Lin K, He D, Teng H, Manyam G, Zhang Z, Liu W, Lee HRL, Tang X, He W, Islam N, Jain A, Chiu Y, Cao S, Diao Y, Meyer-Gauen S, Höök M, Malovannaya A, Li W, Hu M, Wang W, Xu H, Kopetz S, Chen Y. Zheng C, et al. Among authors: wei y. Nat Struct Mol Biol. 2023 Dec;30(12):1878-1892. doi: 10.1038/s41594-023-01117-1. Epub 2023 Nov 6. Nat Struct Mol Biol. 2023. PMID: 37932451 Free PMC article.

10

Integrated multi-omics analyses identify anti-viral host factors and pathways controlling SARS-CoV-2 infection.

Hou J, Wei Y, Zou J, Jaffery R, Sun L, Liang S, Zheng N, Guerrero AM, Egan NA, Bohat R, Chen S, Zheng C, Mao X, Yi SS, Chen K, McGrail DJ, Sahni N, Shi PY, Chen Y, Xie X, Peng W. Hou J, et al. Among authors: wei y. Nat Commun. 2024 Jan 2;15(1):109. doi: 10.1038/s41467-023-44175-1. Nat Commun. 2024. PMID: 38168026 Free PMC article.

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