Xu Q - Search Results

1

Puromycin Prodrug Activation by Thioredoxin Reductase Overcomes Its Promiscuous Cytotoxicity.

Chang B, Xu Q, Guo H, Zhong M, Shen R, Zhao L, Zhao J, Ma T, Chu Y, Zhang J, Fang J. Chang B, et al. Among authors: xu q. J Med Chem. 2023 Mar 9;66(5):3250-3261. doi: 10.1021/acs.jmedchem.2c01509. Epub 2023 Mar 1. J Med Chem. 2023. PMID: 36855911

2

Onopordopicrin from the new genus Shangwua as a novel thioredoxin reductase inhibitor to induce oxidative stress-mediated tumor cell apoptosis.

Zhang J, Zheng ZQ, Xu Q, Li Y, Gao K, Fang J. Zhang J, et al. Among authors: xu q. J Enzyme Inhib Med Chem. 2021 Dec;36(1):790-801. doi: 10.1080/14756366.2021.1899169. J Enzyme Inhib Med Chem. 2021. PMID: 33733960 Free PMC article.

3

Structural Modification of Aminophenylarsenoxides Generates Candidates for Leukemia Treatment via Thioredoxin Reductase Inhibition.

Song ZL, Zhang J, Xu Q, Shi D, Yao X, Fang J. Song ZL, et al. Among authors: xu q. J Med Chem. 2021 Nov 11;64(21):16132-16146. doi: 10.1021/acs.jmedchem.1c01441. Epub 2021 Oct 27. J Med Chem. 2021. PMID: 34704769

4

Integration of a Diselenide Unit Generates Fluorogenic Camptothecin Prodrugs with Improved Cytotoxicity to Cancer Cells.

Zhao J, Wang Z, Zhong M, Xu Q, Li X, Chang B, Fang J. Zhao J, et al. Among authors: xu q. J Med Chem. 2021 Dec 23;64(24):17979-17991. doi: 10.1021/acs.jmedchem.1c01362. Epub 2021 Dec 1. J Med Chem. 2021. PMID: 34852457

5

Inhibition of Thioredoxin Reductase by Santamarine Conferring Anticancer Effect in HeLa Cells.

Zhang J, Xu Q, Yang HY, Yang M, Fang J, Gao K. Zhang J, et al. Among authors: xu q. Front Mol Biosci. 2021 Aug 18;8:710676. doi: 10.3389/fmolb.2021.710676. eCollection 2021. Front Mol Biosci. 2021. PMID: 34485384 Free PMC article.

6

Inhibition of thioredoxin reductase by natural anticancer candidate β-lapachone accounts for triggering redox activation-mediated HL-60 cell apoptosis.

Zhang J, Xu Q, Ma D. Zhang J, et al. Among authors: xu q. Free Radic Biol Med. 2022 Feb 20;180:244-252. doi: 10.1016/j.freeradbiomed.2022.01.019. Epub 2022 Jan 25. Free Radic Biol Med. 2022. PMID: 35091063

7

Novel strategies for targeting the thioredoxin system for cancer therapy.

Xu Q, Zhang J. Xu Q, et al. Expert Opin Drug Discov. 2022 May;17(5):437-442. doi: 10.1080/17460441.2022.2045270. Epub 2022 Feb 27. Expert Opin Drug Discov. 2022. PMID: 35193453

8

Revealing PACMA 31 as a new chemical type TrxR inhibitor to promote cancer cell apoptosis.

Xu Q, Zhang J, Zhao Z, Chu Y, Fang J. Xu Q, et al. Biochim Biophys Acta Mol Cell Res. 2022 Oct;1869(10):119323. doi: 10.1016/j.bbamcr.2022.119323. Epub 2022 Jul 4. Biochim Biophys Acta Mol Cell Res. 2022. PMID: 35793738 Free article.

9

(±)-Alternamgin, a Pair of Enantiomeric Polyketides, from the Endophytic Fungi Alternaria sp. MG1.

Wu JC, Hou Y, Xu Q, Jin XJ, Chen Y, Fang J, Hu B, Wu QX. Wu JC, et al. Among authors: xu q. Org Lett. 2019 Mar 1;21(5):1551-1554. doi: 10.1021/acs.orglett.9b00475. Epub 2019 Feb 21. Org Lett. 2019. PMID: 30789736

10

Xanthohumol Analogues as Potent Nrf2 Activators against Oxidative Stress Mediated Damages of PC12 Cells.

Bai F, Zhang B, Hou Y, Yao J, Xu Q, Xu J, Fang J. Bai F, et al. Among authors: xu q, xu j. ACS Chem Neurosci. 2019 Jun 19;10(6):2956-2966. doi: 10.1021/acschemneuro.9b00171. Epub 2019 Jun 4. ACS Chem Neurosci. 2019. PMID: 31116948

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