Fang J - Search Results

1

Puromycin Prodrug Activation by Thioredoxin Reductase Overcomes Its Promiscuous Cytotoxicity.

Chang B, Xu Q, Guo H, Zhong M, Shen R, Zhao L, Zhao J, Ma T, Chu Y, Zhang J, Fang J. Chang B, et al. Among authors: fang j. J Med Chem. 2023 Mar 9;66(5):3250-3261. doi: 10.1021/acs.jmedchem.2c01509. Epub 2023 Mar 1. J Med Chem. 2023. PMID: 36855911

2

Antioxidant-based lead discovery for cancer chemoprevention: the case of resveratrol.

Qian YP, Cai YJ, Fan GJ, Wei QY, Yang J, Zheng LF, Li XZ, Fang JG, Zhou B. Qian YP, et al. Among authors: fang jg. J Med Chem. 2009 Apr 9;52(7):1963-74. doi: 10.1021/jm8015415. J Med Chem. 2009. Retraction in: J Med Chem. 2009 Oct 22;52(20):6504. doi: 10.1021/jm901413p PMID: 19271734 Retracted.

3

Dithiaarsanes induce oxidative stress-mediated apoptosis in HL-60 cells by selectively targeting thioredoxin reductase.

Liu Y, Duan D, Yao J, Zhang B, Peng S, Ma H, Song Y, Fang J. Liu Y, et al. Among authors: fang j. J Med Chem. 2014 Jun 26;57(12):5203-11. doi: 10.1021/jm500221p. Epub 2014 Jun 11. J Med Chem. 2014. PMID: 24867309

4

Synthesis of xanthohumol analogues and discovery of potent thioredoxin reductase inhibitor as potential anticancer agent.

Zhang B, Duan D, Ge C, Yao J, Liu Y, Li X, Fang J. Zhang B, et al. Among authors: fang j. J Med Chem. 2015 Feb 26;58(4):1795-805. doi: 10.1021/jm5016507. Epub 2015 Feb 6. J Med Chem. 2015. PMID: 25629304

5

Synthesis of piperlongumine analogues and discovery of nuclear factor erythroid 2-related factor 2 (Nrf2) activators as potential neuroprotective agents.

Peng S, Zhang B, Meng X, Yao J, Fang J. Peng S, et al. Among authors: fang j. J Med Chem. 2015 Jul 9;58(13):5242-55. doi: 10.1021/acs.jmedchem.5b00410. Epub 2015 Jun 26. J Med Chem. 2015. PMID: 26079183

6

Inhibition of thioredoxin reductase by alantolactone prompts oxidative stress-mediated apoptosis of HeLa cells.

Zhang J, Li Y, Duan D, Yao J, Gao K, Fang J. Zhang J, et al. Among authors: fang j. Biochem Pharmacol. 2016 Feb 15;102:34-44. doi: 10.1016/j.bcp.2015.12.004. Epub 2015 Dec 11. Biochem Pharmacol. 2016. PMID: 26686580

7

Targeting Thioredoxin Reductase by Parthenolide Contributes to Inducing Apoptosis of HeLa Cells.

Duan D, Zhang J, Yao J, Liu Y, Fang J. Duan D, et al. Among authors: fang j. J Biol Chem. 2016 May 6;291(19):10021-31. doi: 10.1074/jbc.M115.700591. Epub 2016 Mar 21. J Biol Chem. 2016. PMID: 27002142 Free PMC article.

8

Bioassay-guided isolation of dehydrocostus lactone from Saussurea lappa: A new targeted cytosolic thioredoxin reductase anticancer agent.

Yang M, Zhang J, Li Y, Han X, Gao K, Fang J. Yang M, et al. Among authors: fang j. Arch Biochem Biophys. 2016 Oct 1;607:20-6. doi: 10.1016/j.abb.2016.08.008. Epub 2016 Aug 18. Arch Biochem Biophys. 2016. PMID: 27545438

9

A fast response and red emission probe for mammalian thioredoxin reductase.

Ma H, Zhang J, Zhang Z, Liu Y, Fang J. Ma H, et al. Among authors: fang j. Chem Commun (Camb). 2016 Oct 4;52(81):12060-12063. doi: 10.1039/c6cc04984b. Chem Commun (Camb). 2016. PMID: 27709154

10

Securinine disturbs redox homeostasis and elicits oxidative stress-mediated apoptosis via targeting thioredoxin reductase.

Zhang J, Yao J, Peng S, Li X, Fang J. Zhang J, et al. Among authors: fang j. Biochim Biophys Acta Mol Basis Dis. 2017 Jan;1863(1):129-138. doi: 10.1016/j.bbadis.2016.10.019. Epub 2016 Oct 21. Biochim Biophys Acta Mol Basis Dis. 2017. PMID: 27777067 Free article.

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