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Mediator kinase inhibitors suppress triple-negative breast cancer growth and extend tumor suppression by mTOR and AKT inhibitors.
Ding X, Liang J, Sharko AC, Hilimire TA, Li J, Loskutov J, Mack ZT, Ji H, Schools GP, Cai C, Pugacheva EN, Chen M, Roninson IB, Broude EV. Ding X, et al. Among authors: mack zt. Proc Natl Acad Sci U S A. 2024 Nov 19;121(47):e2414501121. doi: 10.1073/pnas.2414501121. Epub 2024 Nov 14. Proc Natl Acad Sci U S A. 2024. PMID: 39541354 Free PMC article.
Mediator kinase inhibition reverses castration resistance of advanced prostate cancer.
Li J, Hilimire TA, Liu Y, Wang L, Liang J, Gyorffy B, Sikirzhytski V, Ji H, Zhang L, Cheng C, Ding X, Kerr KR, Dowling CE, Chumanevich AA, Mack ZT, Schools GP, Lim CU, Ellis L, Zi X, Porter DC, Broude EV, McInnes C, Wilding G, Lilly MB, Roninson IB, Chen M. Li J, et al. Among authors: mack zt. J Clin Invest. 2024 Mar 28;134(10):e176709. doi: 10.1172/JCI176709. J Clin Invest. 2024. PMID: 38546787 Free PMC article.
Inhibition of CDK8/19 Mediator kinase potentiates HER2-targeting drugs and bypasses resistance to these agents in vitro and in vivo.
Ding X, Sharko AC, McDermott MSJ, Schools GP, Chumanevich A, Ji H, Li J, Zhang L, Mack ZT, Sikirzhytski V, Shtutman M, Ivers L, O'Donovan N, Crown J, Győrffy B, Chen M, Roninson IB, Broude EV. Ding X, et al. Among authors: mack zt. Proc Natl Acad Sci U S A. 2022 Aug 9;119(32):e2201073119. doi: 10.1073/pnas.2201073119. Epub 2022 Aug 1. Proc Natl Acad Sci U S A. 2022. PMID: 35914167 Free PMC article.
Pathology in Practice.
Mack ZE, Armwood AR, Howerth EW. Mack ZE, et al. J Am Vet Med Assoc. 2021 Dec 15;259(S2):1-4. doi: 10.2460/javma.19.07.0356. J Am Vet Med Assoc. 2021. PMID: 34910678 Free article.
16 results