Löber S - Search Results

1

Discovery of 2-Aminopyrimidines as Potent Agonists for the Bitter Taste Receptor TAS2R14.

Waterloo L, Hübner H, Fierro F, Pfeiffer T, Brox R, Löber S, Weikert D, Niv MY, Gmeiner P. Waterloo L, et al. Among authors: lober s. J Med Chem. 2023 Mar 9;66(5):3499-3521. doi: 10.1021/acs.jmedchem.2c01997. Epub 2023 Feb 27. J Med Chem. 2023. PMID: 36847646

2

Epidermal growth factor and prostaglandin E(2) accelerate mucosal recovery from stress-induced gastric lesions via inhibition of apoptosis.

Konturek PC, Brzozowski T, Duda A, Kwiecien S, Löber S, Dembinski A, Hahn EG, Konturek SJ. Konturek PC, et al. Among authors: lober s. J Physiol Paris. 2001 Jan-Dec;95(1-6):361-7. doi: 10.1016/s0928-4257(01)00049-3. J Physiol Paris. 2001. PMID: 11595461

3

Azaindole derivatives with high affinity for the dopamine D4 receptor: synthesis, ligand binding studies and comparison of molecular electrostatic potential maps.

Löber S, Hübner H, Gmeiner P. Löber S, et al. Bioorg Med Chem Lett. 1999 Jan 4;9(1):97-102. doi: 10.1016/s0960-894x(98)00692-1. Bioorg Med Chem Lett. 1999. PMID: 9990464

4

Rationally based efficacy tuning of selective dopamine d4 receptor ligands leading to the complete antagonist 2-[4-(4-chlorophenyl)piperazin-1-ylmethyl]pyrazolo[1,5-a]pyridine (FAUC 213).

Löber S, Hübner H, Utz W, Gmeiner P. Löber S, et al. J Med Chem. 2001 Aug 16;44(17):2691-4. doi: 10.1021/jm015522j. J Med Chem. 2001. PMID: 11495580

5

Di- and trisubstituted pyrazolo[1,5-a]pyridine derivatives: synthesis, dopamine receptor binding and ligand efficacy.

Löber S, Aboul-Fadl T, Hübner H, Gmeiner P. Löber S, et al. Bioorg Med Chem Lett. 2002 Feb 25;12(4):633-6. doi: 10.1016/s0960-894x(01)00814-9. Bioorg Med Chem Lett. 2002. PMID: 11844688

6

Fused azaindole derivatives: molecular design, synthesis and in vitro pharmacology leading to the preferential dopamine D3 receptor agonist FAUC 725.

Löber S, Hübner H, Gmeiner P. Löber S, et al. Bioorg Med Chem Lett. 2002 Sep 2;12(17):2377-80. doi: 10.1016/s0960-894x(02)00390-6. Bioorg Med Chem Lett. 2002. PMID: 12161137

7

Click linker: efficient and high-yielding synthesis of a new family of SPOS resins by 1,3-dipolar cycloaddition.

Löber S, Rodriguez-Loaiza P, Gmeiner P. Löber S, et al. Org Lett. 2003 May 15;5(10):1753-5. doi: 10.1021/ol034520l. Org Lett. 2003. PMID: 12735769

8

Synthesis and radioiodination of selective ligands for the dopamine D3 receptor subtype.

Hocke C, Prante O, Löber S, Hübner H, Gmeiner P, Kuwert T. Hocke C, et al. Among authors: lober s. Bioorg Med Chem Lett. 2004 Aug 2;14(15):3963-6. doi: 10.1016/j.bmcl.2004.05.052. Bioorg Med Chem Lett. 2004. PMID: 15225707

9

Parallel synthesis and biological screening of dopamine receptor ligands taking advantage of a click chemistry based BAL linker.

Bettinetti L, Löber S, Hübner H, Gmeiner P. Bettinetti L, et al. Among authors: lober s. J Comb Chem. 2005 Mar-Apr;7(2):309-16. doi: 10.1021/cc049860s. J Comb Chem. 2005. PMID: 15762761

10

Synthesis and evaluation of 18F-labeled dopamine D3 receptor ligands as potential PET imaging agents.

Hocke C, Prante O, Löber S, Hübner H, Gmeiner P, Kuwert T. Hocke C, et al. Among authors: lober s. Bioorg Med Chem Lett. 2005 Nov 1;15(21):4819-23. doi: 10.1016/j.bmcl.2005.07.037. Bioorg Med Chem Lett. 2005. PMID: 16139501

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