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NRF2 activation induces NADH-reductive stress, providing a metabolic vulnerability in lung cancer.
Weiss-Sadan T, Ge M, Hayashi M, Gohar M, Yao CH, de Groot A, Harry S, Carlin A, Fischer H, Shi L, Wei TY, Adelmann CH, Wolf K, Vornbäumen T, Dürr BR, Takahashi M, Richter M, Zhang J, Yang TY, Vijay V, Fisher DE, Hata AN, Haigis MC, Mostoslavsky R, Bardeesy N, Papagiannakopoulos T, Bar-Peled L. Weiss-Sadan T, et al. Among authors: mostoslavsky r. Cell Metab. 2023 Mar 7;35(3):487-503.e7. doi: 10.1016/j.cmet.2023.01.012. Epub 2023 Feb 24. Cell Metab. 2023. PMID: 36841242 Free PMC article.
DNA demethylation: turning genes on.
Bergman Y, Mostoslavsky R. Bergman Y, et al. Among authors: mostoslavsky r. Biol Chem. 1998 Apr-May;379(4-5):401-7. doi: 10.1515/bchm.1998.379.4-5.401. Biol Chem. 1998. PMID: 9628330 Review.
120 results