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Page 1
The Mechanism of Enantioselective Neurosteroid Actions on GABAA Receptors.
Tateiwa H, Chintala SM, Chen Z, Wang L, Amtashar F, Bracamontes J, Germann AL, Pierce SR, Covey DF, Akk G, Evers AS. Tateiwa H, et al. Among authors: covey df. Biomolecules. 2023 Feb 9;13(2):341. doi: 10.3390/biom13020341. Biomolecules. 2023. PMID: 36830708 Free PMC article.
Neurosteroid enantiomers as potentially novel neurotherapeutics.
Covey DF, Evers AS, Izumi Y, Maguire JL, Mennerick SJ, Zorumski CF. Covey DF, et al. Neurosci Biobehav Rev. 2023 Jun;149:105191. doi: 10.1016/j.neubiorev.2023.105191. Epub 2023 Apr 20. Neurosci Biobehav Rev. 2023. PMID: 37085023 Free PMC article. Review.
GPR161 structure uncovers the redundant role of sterol-regulated ciliary cAMP signaling in the Hedgehog pathway.
Hoppe N, Harrison S, Hwang SH, Chen Z, Karelina M, Deshpande I, Suomivuori CM, Palicharla VR, Berry SP, Tschaikner P, Regele D, Covey DF, Stefan E, Marks DS, Reiter J, Dror RO, Evers AS, Mukhopadhyay S, Manglik A. Hoppe N, et al. Among authors: covey df. bioRxiv [Preprint]. 2023 May 24:2023.05.23.540554. doi: 10.1101/2023.05.23.540554. bioRxiv. 2023. Update in: Nat Struct Mol Biol. 2024 Apr;31(4):667-677. doi: 10.1038/s41594-024-01223-8 PMID: 37292845 Free PMC article. Updated. Preprint.
Direct measurements of neurosteroid binding to specific sites on GABAA receptors.
Chintala SM, Tateiwa H, Qian M, Xu Y, Amtashar F, Chen ZW, Kirkpatrick CC, Bracamontes J, Germann AL, Akk G, Covey DF, Evers AS. Chintala SM, et al. Among authors: covey df. Br J Pharmacol. 2024 Nov;181(21):4229-4244. doi: 10.1111/bph.16490. Epub 2024 Jul 8. Br J Pharmacol. 2024. PMID: 38978389 Free PMC article.
Sex-specific hypnotic effects of the neuroactive steroid (3β,5β,17β)-3-hydroxyandrostane-17-carbonitrile are mediated by peripheral metabolism into an active hypnotic steroid.
Manzella FM, Cabrera OH, Wilkey D, Fine-Raquet B, Klawitter J, Krishnan K, Covey DF, Jevtovic-Todorovic V, Todorovic SM. Manzella FM, et al. Among authors: covey df. Br J Anaesth. 2023 Feb;130(2):154-164. doi: 10.1016/j.bja.2022.09.025. Epub 2022 Nov 22. Br J Anaesth. 2023. PMID: 36428160 Free PMC article.
5β-Dihydrosteroids: Formation and Properties.
Penning TM, Covey DF. Penning TM, et al. Among authors: covey df. Int J Mol Sci. 2024 Aug 14;25(16):8857. doi: 10.3390/ijms25168857. Int J Mol Sci. 2024. PMID: 39201544 Free PMC article. Review.
343 results