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Granulin loss of function in human mature brain organoids implicates astrocytes in TDP-43 pathology.
de Majo M, Koontz M, Marsan E, Salinas N, Ramsey A, Kuo YM, Seo K, Li H, Dräger N, Leng K, Gonzales SL, Kurnellas M, Miyaoka Y, Klim JR, Kampmann M, Ward ME, Huang EJ, Ullian EM. de Majo M, et al. Among authors: seo k. Stem Cell Reports. 2023 Mar 14;18(3):706-719. doi: 10.1016/j.stemcr.2023.01.012. Epub 2023 Feb 23. Stem Cell Reports. 2023. PMID: 36827976 Free PMC article.
CRISPRi-based radiation modifier screen identifies long non-coding RNA therapeutic targets in glioma.
Liu SJ, Malatesta M, Lien BV, Saha P, Thombare SS, Hong SJ, Pedraza L, Koontz M, Seo K, Horlbeck MA, He D, Birk HS, Jain M, Olsen HE, Akeson M, Weissman JS, Monje M, Gupta N, Raleigh DR, Ullian EM, Lim DA. Liu SJ, et al. Among authors: seo k. Genome Biol. 2020 Mar 31;21(1):83. doi: 10.1186/s13059-020-01995-4. Genome Biol. 2020. PMID: 32234056 Free PMC article.
Multiplatform genomic profiling and magnetic resonance imaging identify mechanisms underlying intratumor heterogeneity in meningioma.
Magill ST, Vasudevan HN, Seo K, Villanueva-Meyer JE, Choudhury A, John Liu S, Pekmezci M, Findakly S, Hilz S, Lastella S, Demaree B, Braunstein SE, Bush NAO, Aghi MK, Theodosopoulos PV, Sneed PK, Abate AR, Berger MS, McDermott MW, Lim DA, Ullian EM, Costello JF, Raleigh DR. Magill ST, et al. Among authors: seo k. Nat Commun. 2020 Sep 23;11(1):4803. doi: 10.1038/s41467-020-18582-7. Nat Commun. 2020. PMID: 32968068 Free PMC article.
Multiplatform Molecular Profiling Reveals Epigenomic Intratumor Heterogeneity in Ependymoma.
Liu SJ, Magill ST, Vasudevan HN, Hilz S, Villanueva-Meyer JE, Lastella S, Daggubati V, Spatz J, Choudhury A, Orr BA, Demaree B, Seo K, Ferris SP, Abate AR, Oberheim Bush NA, Bollen AW, McDermott MW, Costello JF, Raleigh DR. Liu SJ, et al. Among authors: seo k. Cell Rep. 2020 Feb 4;30(5):1300-1309.e5. doi: 10.1016/j.celrep.2020.01.018. Cell Rep. 2020. PMID: 32023450 Free PMC article.
Meningioma DNA methylation groups identify biological drivers and therapeutic vulnerabilities.
Choudhury A, Magill ST, Eaton CD, Prager BC, Chen WC, Cady MA, Seo K, Lucas CG, Casey-Clyde TJ, Vasudevan HN, Liu SJ, Villanueva-Meyer JE, Lam TC, Pu JK, Li LF, Leung GK, Swaney DL, Zhang MY, Chan JW, Qiu Z, Martin MV, Susko MS, Braunstein SE, Bush NAO, Schulte JD, Butowski N, Sneed PK, Berger MS, Krogan NJ, Perry A, Phillips JJ, Solomon DA, Costello JF, McDermott MW, Rich JN, Raleigh DR. Choudhury A, et al. Among authors: seo k. Nat Genet. 2022 May;54(5):649-659. doi: 10.1038/s41588-022-01061-8. Epub 2022 May 9. Nat Genet. 2022. PMID: 35534562 Free PMC article.
A case (report) for mechanistic validation of meningioma molecular therapies.
Nguyen MP, Seo K, Eaton CD, Lucas CG, Chen WC, Choudhury A, Young JS, Raleigh DR. Nguyen MP, et al. Among authors: seo k. Neurooncol Adv. 2022 Oct 8;4(1):vdac162. doi: 10.1093/noajnl/vdac162. eCollection 2022 Jan-Dec. Neurooncol Adv. 2022. PMID: 36382111 Free PMC article. No abstract available.
Spatial genomic, biochemical and cellular mechanisms underlying meningioma heterogeneity and evolution.
Lucas CG, Mirchia K, Seo K, Najem H, Chen WC, Zakimi N, Foster K, Eaton CD, Cady MA, Choudhury A, Liu SJ, Phillips JJ, Magill ST, Horbinski CM, Solomon DA, Perry A, Vasudevan HN, Heimberger AB, Raleigh DR. Lucas CG, et al. Among authors: seo k. Nat Genet. 2024 Jun;56(6):1121-1133. doi: 10.1038/s41588-024-01747-1. Epub 2024 May 17. Nat Genet. 2024. PMID: 38760638 Free PMC article.
Spatial genomic, biochemical, and cellular mechanisms drive meningioma heterogeneity and evolution.
Lucas CH, Mirchia K, Seo K, Najem H, Chen W, Zakimi N, Choudhury A, Liu SJ, Phillips J, Magill S, Horbinski C, Solomon D, Perry A, Vasudevan H, Heimberger A, Raleigh D. Lucas CH, et al. Among authors: seo k. Res Sq [Preprint]. 2023 May 15:rs.3.rs-2921804. doi: 10.21203/rs.3.rs-2921804/v1. Res Sq. 2023. Update in: Nat Genet. 2024 Jun;56(6):1121-1133. doi: 10.1038/s41588-024-01747-1 PMID: 37292686 Free PMC article. Updated. Preprint.
2,637 results