CDH1 loss promotes diffuse-type gastric cancer tumorigenesis via epigenetic reprogramming and immune evasion.
Zou G, Huang Y, Zhang S, Ko KP, Kim B, Zhang J, Venkatesan V, Pizzi MP, Fan Y, Jun S, Niu N, Wang H, Song S, Ajani JA, Park JI.
Zou G, et al. Among authors: ko kp.
bioRxiv [Preprint]. 2023 Oct 11:2023.03.23.533976. doi: 10.1101/2023.03.23.533976.
bioRxiv. 2023.
PMID: 36993615
Free PMC article.
Updated.
Preprint.
Genetically engineered murine gastric organoids showed that Cdh1 knock-out (KO), Kras(G12D), Trp53 KO (EKP) accelerates tumorigenesis with immune evasion compared to Kras(G12D), Trp53 KO (KP). ...
Genetically engineered murine gastric organoids showed that Cdh1 knock-out (KO), Kras(G12D), Trp53 KO (EKP) accelerates tumori …